CKD Management Post-AKI: The Role of Biomarkers

Morgans, Heather A.; Warady, Bradley A.

doi:10.1007/978-981-33-4554-6_17

Cited by 1 publication

(1 citation statement)

References 27 publications

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“…The spectrum of AKI biomarkers in the pediatric population has been reviewed extensively elsewhere [ 11 , 12 , 13 , 14 ]. However, their implementation is restricted to small groups of patients and the results, rather of scientific than diagnostic value, could not modify the strategy of improvement for pediatric AKI [ 15 ].…”

Section: Markers Of Injurymentioning

confidence: 99%

Current Concepts of Pediatric Acute Kidney Injury—Are We Ready to Translate Them into Everyday Practice?

Musiał

2021

JCM

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Pediatric acute kidney injury (AKI) is a major cause of morbidity and mortality in children undergoing interventional procedures. The review summarizes current classifications of AKI and acute kidney disease (AKD), as well as systematizes the knowledge on pathophysiology of kidney injury, with a special focus on renal functional reserve and tubuloglomerular feedback. The aim of this review is also to show the state-of-the-art in methods assessing risk and prognosis by discussing the potential role of risk stratification strategies, taking into account both glomerular function and clinical settings conditioned by fluid overload, urine output, or drug nephrotoxicity. The last task is to suggest careful assessment of eGFR as a surrogate marker of renal functional reserve and implementation of point-of-care testing, available in the case of biomarkers like NGAL and [IGFBP-7] × [TIMP-2] product, into everyday practice in patients at risk of AKI due to planned invasive procedures or treatment.

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Section: Markers Of Injurymentioning

confidence: 99%

Current Concepts of Pediatric Acute Kidney Injury—Are We Ready to Translate Them into Everyday Practice?

Musiał

2021

JCM

View full text Add to dashboard Cite

show abstract

CKD Management Post-AKI: The Role of Biomarkers

Cited by 1 publication

References 27 publications

Current Concepts of Pediatric Acute Kidney Injury—Are We Ready to Translate Them into Everyday Practice?

Current Concepts of Pediatric Acute Kidney Injury—Are We Ready to Translate Them into Everyday Practice?

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