Circumventing aglycon transfer en route to the synthesis of pentasaccharide thioglycoside donor for the chain extension of Plesiomonas shigelloides strain 302-73 (serotype O1) repeating unit

Total Synthesis of the Conjugation-Ready Tetrasaccharide Repeating Unit of Shewanella japonica Type Strain KMM 3299T

“…In this reaction, the donor was decomposed, and a small amount of aglycon transfer of SPh from acceptor 8 to donor 17 was observed (Scheme ). It is known that the arming effect of acceptor and donor can increase the aglycon transfer product . Taking clues from this, we thought to use a disarmed acceptor.…”