Circumscribed Myxedema of the Skin

Circumscribed Myxedema

“…This became worse during the summer and gradually cleared up after the frost. In 1930In , 1931In and 1932 he suffered from a repetition of the same process. He stated, however, that at one time during the height of the eruption, when it was so bad that it necessi¬ tated the discontinuance of his work, the eruption temporarily cleared up only to relapse on the resumption of his occupation.…”

Ultrastructure of localized myxedema

“…They supposed that the fibroblasts are the origin of hyaluronic acid. ln the mucinous areas, stellate cells have been found (28). Korting et al (25) dem-onstrated alcian blue-positive, metachromatic granules in dermal cells which they distinguished from fibroblasts naming them "mucoblasts".…”