Circumpolar maternal blood contaminant survey, 1994–1997 organochlorine compounds

Oostdam, J C Van; Dewailly, Éric; Gilman, Andrew P.; Hansen, Jens Christian; Odland, Jon Øyvind; Chashchin, Valery; Berner, James; Butler-Walker, J; Lagerkvist, Bengt; Ólafsdóttir, Kristín; Soininen, Leena; Bjerregard, P; Klopov, V. I.; Weber, Jean-Philippe

doi:10.1016/j.scitotenv.2004.02.028

Cited by 70 publications

(44 citation statements)

References 19 publications

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“…Interestingly, PCB levels in Brazilian delivering women were higher than those recently reported in the plasma of delivering women in South Africa and Vietnam Röllin et al, 2009). They were however lower than those reported by Van Oostdam et al (2004) in comparable populations residing in Canada, the Netherland and Spain. The imbalanced distribution of this large group of 209 PCB congenersall of which have different physiochemical properties, different ranges of persistence and biological activity; -is important information that can possibly contribute to the global debate (Birnbaum and StaskalWikoff, 2010).…”

Section: Discussioncontrasting

confidence: 62%

Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Rudge

Sandanger

Röllin

et al. 2012

Environment International

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2012Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of Sao Paulo State, Brazil ENVIRONMENT INTERNATIONAL, OXFORD, v. 40, Persistent organic pollutants (POPs) present in the living environment are thought to have detrimental health effects on the population, with pregnant women and the developing foetus being at highest risk. We report on the levels of selected POPs in maternal blood of 155 delivering women residing in seven regions within the São Paulo State, Brazil. The following selected POPs were measured in the maternal whole blood: 12 polychlorinated biphenyls (PCBs) congeners (IUPAC Nos. 99, 101, 118, 138, 153, 156, 163, 170, 180, 183, 187, 194); dichlordiphenyltrichloroethane p,p′-DDT, diphenyldichloroethylene p,p′-DDE and other pesticides such as hexachlorocyclohexanes (α-HCH, β-HCH, γ-HCH), hexachlorobenzene (HCB), chlordane derivatives cis-chlordane, transchlordane, oxy-chlordane, cis-nonachlor and trans-nonachlor. Statistical comparisons between regions were performed only on compounds having concentrations above LOD in 70% of the samples. PCB118 congener was found to be highest in the industrial site (mean 4.97 ng/g lipids); PCB138 congener concentration was highest in the Urban 3 site (mean 4.27 ng/g lipids) and congener PCB153 was highest in the industrial and Urban 3 sites with mean concentration of 7.2 ng/g lipids and 5.89 ng/g lipids respectively. Large differences in levels of p,p′-DDE between regions were observed with the Urban 3 and industrial sites having the highest concentrations of 645 ng/g lipids and 417 ng/g lipids, respectively; β-HCH was found to be highest in the Rural 1 site; the γ-HCH in Rural 1 and industrial; the HCB in the Rural 1 and industrial sites and oxy-chlordane and t-NC in the Rural 2 sites. An association between levels of some contaminants and maternal age and parity was also found.

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Section: Discussioncontrasting

confidence: 62%

Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Rudge

Sandanger

Röllin

et al. 2012

Environment International

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“…In serum samples obtained in between 1994 and1997 from Inuit women in different Arctic countries, the reported oxychlordane and trans-nonachlor geometric mean levels from Canada and Greenland groups were about threefold to fivefold higher than among females in this Report (van Oostdam et al, 2004). A small sample of Polish women had mean levels of oxychlordane and trans-nonachlor that were about fivefold lower than in females in the NHANES subsample (Jaraczweska et al, 2006.…”

Section: Biomonitoring Informationmentioning

confidence: 75%

Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data

Huber

Blount

Mage

et al. 2010

J Expo Sci Environ Epidemiol

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“…The mean ∑ 14 PCBs concentrations in the samples from Weifang (4.3 ng/g lipid) and Nanning (1.9 ng/g lipid) were both lower than the concentrations that have been found in serum samples from Guangdong, China (sum of the concentrations of 23 congeners 65 ng/g lipid) [51] and Shanghai, China (sum of the concentrations of 20 congeners 70 ng/g lipid) [61], and much lower than the concentrations that have been found in serum samples from UK (sum of the concentrations of 23 congeners 130 ng/g lipid) [53] and Canada (sum of the concentrations 14 congeners 180 ng/g lipid) [62].…”

Section: The Concentrations Of the Main Pcb Congeners (Shown Inmentioning

confidence: 76%

Polybrominated diphenyl ether, polychlorinated biphenyl, and dechlorane plus concentrations in human serum, and their relationships with thyroid hormones.

Wang¹,

Xu²,

Li³

et al. 2017

Environ Risk Assess Remediat

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Persistent halogenated organic compounds, including polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and dechlorane plus (DP), were determined in human serum collected in Weifang and Nanning, China, and the relationships between their concentrations and thyroid hormone concentrations were determined. The total PBDE (∑ 10 PBDEs), total PCB (∑ 14 PCBs), and total DP (∑DP) concentrations were higher in Weifang (medians 220, 4.3, and 2.2 ng/g lipid, respectively) than in Nanning (medians 180, 1.9, and 1.5 ng/g lipid, respectively). The donors' ages correlated with ∑ 14 PCBs but not with ∑ 10 PBDEs or ∑DP in Weifang. Age positively correlated with ∑ 10 PBDEs but not ∑ 14 PCBs and ∑DP in Nanning. The correlations between the individual PBDE, PCB, and DP congener and thyroid hormone concentrations were analyzed by stepwise multiple linear regression after log 2 -transforming the variables. Triiodothyronine (T3) concentrations were associated with BDE-99 concentrations and ∑DP in Weifang but with BDE-153 concentrations and ∑ 10 PBDEs in Nanning. A positive correlation was found, for the first time, between anti-DP and free-T3 concentrations in Weifang, but free-T3 concentrations correlated with PCB-118 and PCB-170 concentrations in Nanning. Thyroxine (T4) concentrations correlated with total dioxin-like PCB concentrations in Weifang but with PCB-156 concentrations in Nanning. No significant correlations were found between the analyte and free-T4 concentrations in Weifang, but negative correlations were found between free-T4 and total dioxin-like PCB and BDE-190 concentrations in Nanning. No significant correlations were found between the analyte and thyroid-stimulating hormone (TSH) concentrations in Weifang but negative correlations were found between ∑ 10 PBDEs and the TSH concentrations in Nanning. The correlations between the analyte and thyroid hormone concentrations followed different trends in Weifang and Nanning but were similar to those that have been found in animal and epidemiological studies. AbstractPolybrominated diphenyl ether, polychlorinated biphenyl, and dechlorane plus concentrations in human serum, and their relationships with thyroid hormones.

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Circumpolar maternal blood contaminant survey, 1994–1997 organochlorine compounds

Cited by 70 publications

References 19 publications

Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Levels of selected persistent organic pollutants in blood from delivering women in seven selected areas of São Paulo State, Brazil

Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data

Polybrominated diphenyl ether, polychlorinated biphenyl, and dechlorane plus concentrations in human serum, and their relationships with thyroid hormones.

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