Circumorificial plasmacytosis/plasma cell orificial mucositis: a case series and a review of the literature

Plasma cell mucositis of the larynx

“…21 It also reported the novel use of subcutaneous adalimumab with full resolution of symptoms, and this may point to a potential future treatment option. 21 In any case, the importance of timely and effective medical treatments is highlighted by reports of disease progression requiring surgical intervention. A rare case by Minstry et al discussed the complication of supraglottic stenosis requiring balloon dilatation, 22 and other cases have noted the requirement of tracheostomy to secure an unsafe airway.…”

“…A recent case series suggested betamethasone mouthwash and cream may offer some improvement in oral mucositis . It also reported the novel use of subcutaneous adalimumab with full resolution of symptoms, and this may point to a potential future treatment option . In any case, the importance of timely and effective medical treatments is highlighted by reports of disease progression requiring surgical intervention.…”

Two cases of chronic oral ulcers effectively treated with systemic corticosteroid therapy: Circumorificial plasmacytosis and traumatic ulcerative granuloma with stromal eosinophilia

“…There is no consensus on the treatment for CP. Topical, intralesional or systemic steroids are usually chosen as the first‐line therapy . Topical tacrolimus, topical fusidic acid ointment and adalimumab have been reported as other effective options .…”

“…Topical, intralesional or systemic steroids are usually chosen as the first-line therapy. 4 Topical tacrolimus, topical fusidic acid ointment and adalimumab have been reported as other effective options. [4][5][6] The development to plasma cell neoplasm is quite rare, and only one patient has been reported to have developed plasma cell neoplasm.…”

“…4 Topical tacrolimus, topical fusidic acid ointment and adalimumab have been reported as other effective options. [4][5][6] The development to plasma cell neoplasm is quite rare, and only one patient has been reported to have developed plasma cell neoplasm. 7 Although the deep ulcer in case 1 was atypical as CP, self-injury was suspected to have exacerbated the ulcer.…”