Circumcision Status is Not Associated with Condom Use and Prevalence of Sexually Transmitted Infections Among Young Black MSM

Crosby, Richard A.; Graham, Cynthia A.; Mena, Leandro; Yarber, William L.; Sanders, Stephanie A.; Milhausen, Robin R.; Geter, Angelica

doi:10.1007/s10461-015-1212-x

Cited by 8 publications

(8 citation statements)

References 12 publications

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“…33 17 reported STIs other than HIV as outcomes, 16,20,23,33,35,36,40,43,[46][47][48][49][50]65,68,70,74 and 12 reported both HIV infection and other STIs as outcomes. 17,25,27,32,34,39,41,[71][72][73]79,87,88,91 Four studies-two for HIV 15, 29 and two for other STIs 65,70were excluded from the meta-analysis because they did not report data necessary to calculate ORs (figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…Cumulative meta-analysis Men (n) Kreiss et al (1993) 73 Lafferty et al (1997) 74 Mor et al (2007) 79 Templeton et al (2009) 88 Jameson et al (2010) 71 Jozkowski et al (2010) 72 Zou et al (2010) 91 Goldstone et al (2011) 68 Mor et al (2012) 16 van Aar et al (2013) 27 van Aar et al (2013) 27 Pando et al (2013) 25 Canadas et al (2013) 20 Hu et al (2013) 23 Hu et al (2013) 23 Zeng et al (2014) 32 Zou et al (2014) 33 Liu et al (2015) 34 Okafor et al (2015) 35 Rebe et al (2015) 36 Qian et al (2016) 41 Crosby et al (2016) 39 Lee et al (2016) 40 Somia et al (2016) 43 Raghavendran et al (2017) 47 Qian et al (2017) 46 Tian et al (2017) 48 Xin et al (2017) 50 Wahome et al (2017) 49 Overall Heterogeneity I 2 =8% 496 744 20 832 1396 3828 24 900 390 589 448 310 453 482 450 204 446 520 163 690 423 200 1095 346 133 49 274 650 500 88 312 61 411…”

Section: Meta-analysismentioning

confidence: 99%

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Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data

Yuan

Fitzpatrick

et al. 2019

The Lancet Global Health

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Background Men who have sex with men (MSM) are disproportionately affected by HIV and other sexually transmitted infections (STIs) worldwide. Previous reviews investigating the role of circumcision in preventing HIV and other STIs among MSM were inconclusive. Many new studies have emerged in the past decade. To inform global prevention strategies for HIV and other STIs among MSM, we reviewed all available evidence on the associations between circumcision and HIV and other STIs among MSM.Methods In this systematic review and meta-analysis, we searched PubMed, Web of Science, BioMed Central, Scopus, ResearchGate, Cochrane Library, Embase, PsycINFO, Google Scholar, and websites of international HIV and STI conferences for studies published before March 8, 2018. Interventional or observational studies containing original quantitative data describing associations between circumcision and incident or prevalent infection of HIV and other STIs among MSM were included. Studies were excluded if MSM could not be distinguished from men who have sex with women only. We calculated pooled odds ratios (ORs) and their 95% CIs using random-effect models. We assessed risk of bias using the Newcastle-Ottawa scale. (0·99, 0·90-1·09; k=20; I²=40%). Circumcision was associated with reduced odds of herpes simplex virus (HSV) infection among MSM overall (0·84, 0·75-0·95; k=5; I²=0%) and penile human papillomavirus (HPV) infection among HIV-infected MSM (0·71, 0·51-0·99; k=3; I²=0%). Findings We identified 62 observational studies including 119 248 MSM. Circumcision was associated with 23% reduced odds of HIV infection among MSM overall (OR 0·77, 95% CI 0·67-0·89; number of estimates [k]=45; heterogeneity I²=77%). Circumcision was protective against HIV infection among MSM in countries of low and middle income (0·58, 0·41-0·83; k=23; I²=77%) but not among MSM in high-income countries Interpretation We found evidence that circumcision is likely to protect MSM from HIV infection, particularly in countries of low and middle income. Circumcision might also protect MSM from HSV and penile HPV infection. MSM should be included in campaigns promoting circumcision among men in countries of low and middle income.In view of the substantial proportion of MSM in countries of low and middle income who also have sex with women, well designed longitudinal studies differentiating MSM only and bisexual men are needed to clarify the effect of circumcision on male-to-male transmission of HIV and other STIs.

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Section: Resultsmentioning

confidence: 99%

Section: Meta-analysismentioning

confidence: 99%

Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data

Yuan

Fitzpatrick

et al. 2019

The Lancet Global Health

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“…111 An investigation involving Afro-American MSM failed to find any difference between those who were circumcised and the uncircumcised in experiencing problems with use of condoms or extent of perceiving condoms as detracting from sexual pleasure. 112 A 2018 small 10-item "penile anatomy and circumcision quiz" by Earp et al of 999 US men circumcised as infants found that most of these circumcised men were satisfied with having been circumcised. 113 But instead of accepting the findings as had been reported by the men, Earp et al suggested that the men had adopted "false beliefs" to "'justify' their genitally altered state."…”

Section: Cohort Studies (Level 2e Grade D)mentioning

confidence: 99%

The Contrasting Evidence Concerning the Effect of Male Circumcision on Sexual Function, Sensation, and Pleasure: A Systematic Review

Morris

Krieger

2020

Sexual Medicine

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Introduction: Active debate concerns whether male circumcision (MC) affects sexual function, penile sensation, or sexual pleasure. Aim: To perform a systematic review examining the effect of MC on these parameters. Methods: PRISMA-compliant searches of PubMed, EMBASE, the Cochrane Library, and Google Scholar were performed, with "circumcision" used together with appropriate search terms. Articles meeting the inclusion criteria were rated for quality by the Scottish Intercollegiate Guidelines Network system. Main Outcome Measure: Evidence rated by quality. Results: Searches identified 46 publications containing original data, as well as 4 systematic reviews (2 with meta-analyses), plus 29 critiques of various studies and 15 author replies, which together comprised a total of 94 publications. There was overall consistency in conclusions arising from high-and moderate-quality survey data in randomized clinical trials, systematic reviews and meta-analyses, physiological studies, large longitudinal studies, and cohort studies in diverse populations. Those studies found MC has no or minimal adverse effect on sexual function, sensation, or pleasure, with some finding improvements. A consensus from physiological and histological studies was that the glans and underside of the shaft, not the foreskin, are involved in neurological pathways mediating erogenous sensation. In contrast to the higher quality evidence, data supporting adverse effects of MC on function, sensation, or pleasure were found to be of low quality, as explained in critiques of those studies. Conclusion: The consensus of the highest quality literature is that MC has minimal or no adverse effect, and in some studies, it has benefits on sexual functions, sensation, satisfaction, and pleasure for males circumcised neonatally or in adulthood.

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“…Crosby & Charnigo specifically provided data relevant to sensation (see their Table 1), and although scores for adverse perceptions were actually higher for uncircumcised men, there was no statistical difference. A subsequent study, of Afro-American MSM, found no difference between men of either MC status in problems with condom use or perception that condoms detracted from sexual pleasure [156]. We therefore strongly dispute the use by H&C of the findings by Crosby and Charnigo as support for their contention that circumcised men avoid condoms because of sensation issues.…”

Section: Condom Usementioning

confidence: 63%

“…Crosby & Charnigo [155], Crosby et al [156] No difference in condom use or number of partners between circumcised and uncircumcised men (review)…”

Section: Supposed Sexual and Physical Harmsmentioning

confidence: 99%

Critical Evaluation of a Survey Claiming “Long-Term Adverse Outcomes from Neonatal Circumcision”*

Bailis¹,

Moreton²,

Morris³

2019

ASM

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We critically evaluate an online "Global survey of circumcision harm" that gauged beliefs of men who thought that their neonatal circumcision had harmed them. Sequential evaluation of the survey data and claims reveal numerous serious flaws that are at odds with strong scientific evidence. Moreover, the one-sided study design and "loaded" survey title meant the findings were not representative of the general population of circumcised males. None of the participants' claimed physical problems were confirmed by a health practitioner. Belief in this seriously flawed survey has potential to cause psychological harm to vulnerable men influenced by anti-circumcision claims, and as such has serious detrimental implications for male sexual health. The survey appears driven less by empiricism and more by psychological forces, as we show in detail. The overwhelming body of high quality medical scientific evidence finds no adverse effect of male circumcision on sexual function and pleasure, but strong evidence for a wide array of lifetime benefits in protection against infections, dermatological problems, and genital cancers. Consistent with the United Nations Convention on the Rights of the Child, children are entitled to low risk procedures that are beneficial to their health. In conclusion, the survey and its uncritical presentation do a disservice to evidence-based medicine, sexual health, mental health, public health, human rights, and pediatric policy development. It should therefore be dismissed as unreliable.

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Circumcision Status is Not Associated with Condom Use and Prevalence of Sexually Transmitted Infections Among Young Black MSM

Cited by 8 publications

References 12 publications

Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data

Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data

The Contrasting Evidence Concerning the Effect of Male Circumcision on Sexual Function, Sensation, and Pleasure: A Systematic Review

Critical Evaluation of a Survey Claiming “Long-Term Adverse Outcomes from Neonatal Circumcision”*

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