Abstract:Background: The first trimester of pregnancy remains an unknown immunological adaptation. Cytokines and syncytiotrophoblast microvesicles (STBM) have been identified as key factors involved in the maternal immune adaptation. This study therefore aims to determine the levels of T helper cell 1 (Th1) and 2 (Th2) associated cytokines TNF-α and IL-6 in relation to the relative concentration of STBM's in maternal circulation. Materials and Methods: Plasma samples from normotensive pregnant women in the first trimes… Show more
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