Circulatory Disturbances Caused by Intestinal Obstruction

Gatch, W. D.; Culbertson, C. G.

doi:10.1097/00000658-193510000-00012

Cited by 32 publications

(5 citation statements)

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“…However, there is apparently a dis crepancy between our present results and those of P r ic e et al [11], who described an enhancement of mesenteric blood flow upon passive gut distension with saline. Parenthetically, it should be noted that the effects of distension whether with saline [1,3,4,7,15] or air [6,14] do not seem to differ as far as diminishing blood flow is concerned. Nevertheless, despite the difference in reported results of enhanced blood flow [11] and reduced blood flow [1,3,4,6,7,8,9,14,15] upon gut distension, there appear to be reasonable explanations.…”

Section: Discussionmentioning

confidence: 99%

“…Parenthetically, it should be noted that the effects of distension whether with saline [1,3,4,7,15] or air [6,14] do not seem to differ as far as diminishing blood flow is concerned. Nevertheless, despite the difference in reported results of enhanced blood flow [11] and reduced blood flow [1,3,4,6,7,8,9,14,15] upon gut distension, there appear to be reasonable explanations. In the experiments by P r ic e et al [11], blood flow of the entire small intestine was measured, whereas the other authors [1,3,4,[6][7][8][9]15] and we recorded only flow to or from a segment with a circum scribed blood supply.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Distension and Acetylcholine on Intestinal Blood Flow <i>in vivo</i>

Brobmann¹,

Jacobson²,

Brecher³

1970

J Vasc Res

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In vivo canine gut segments perfused by branches of the superior mesenteric artery were subjected to increased intraluminal pressure to observe the effects upon arterial inflow, measured with an electromagnetic blood flowmeter, and venous effluent collected by a cannula. Inflation of the intestinal segment with air simultaneously reduced both inflow and outflow. Intra-arterial infusion of acetylcholine increased blood flow, even with intraluminal pressure maintained at 40 mm Hg. Mechanical distension of the gut impedes blood flow, but this effect can be overridden by a vasodilator. These findings correspond to results observed in similar experiments on in vitro gut segments.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effects of Distension and Acetylcholine on Intestinal Blood Flow <i>in vivo</i>

Brobmann¹,

Jacobson²,

Brecher³

1970

J Vasc Res

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“…3 Regardless of the underlying cause, once this torsion occurs initial venous engorgement followed by lack of arterial flow leads to ischemic changes in the bowel, with eventual necrosis and perforation. 15 Clinical features of volvulus depend, in part, on location of the volvulus as well as the degree of obstruction, and viability of the colon. As such, they vary from chronic dysmotility complaints to acute obstruction and perforation.…”

Section: Discussionmentioning

confidence: 99%

Management of colonic volvulus

Kamal

Saad

2011

Ain Shams Journal of Surgery

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Aim: Colonic volvulus is defined as an axial twist of part of the colon along its mesentery of which sigmoid volvulus is the most common & splenic flexure volvulus is the least common. The purpose of this study is to evaluate the clinical features and surgical treatment methods in patients with colonic volvulus.Method : Thirty-six patients operated upon between April 2007 and Mars 2010 were reviewed retrospectively. The demographic data of the patients, clinical features, preoperative radiological and operative findings, type of surgical procedure performed, postoperative complications, mortality and duration of hospital stay after surgery were reviewed.Results : There were 26 male (72%), 10 female patients (28%) and their age ranged from 28 to 72 years with a mean of 53±7.8 years. Most frequent clinical features were abdominal pain, distension and constipation by order of frequency. Hypertension was the most frequent co-morbidity. WBCs were elevated in 32 patients. Plain X-ray was done routinely in every patient with +ve results in 28 patients (77%) & contrast enema was done in 6 patients only. Emergent surgical treatment done in patients with manifestations of peritonitis (30pt, 83%). Intra-operative, sigmoid volvulus was found in 30 pts, caecal volvulus in 3 patients, transverse colon volvulus in 2 pts and one case of splenic flexure volvulus. Decision for operation (Untwisting & fixation (n=3), resection & primary anastomosis (n=10), resection, anastomosis & covering stoma(n=11) and resection & colostomy (n=12), was dependent on intestinal viability, general condition of patient and surgeon's preference. Post operative hospital stay ranged from 5 days to 26 days. It was least in patients underwent resection, anastomosis & covering stoma 8±4.11 and maximum in patient with just detortion & fixation (15±8.53). Post operative complications included post-operative, anastomotic leakage, wound infection, re-operation (Recurrent obstruction) and pulmonary complications. Conclusion : Identifying those patients at the onset of their clinical course of colonic volvulus entails a high index of suspicion & resection with or without primary anastomosis should be the basic principle in management of colonic volvulus as detorsion and fixation carry a high risk of recurrence of the volvulus

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“…Falconer and Gladnikoff (12) have reported that during the absorption period the concentration of alcohol in portal vein blood is considerably higher than in blood from the vena cava. Gatch and Culbertson (13) have shown that the venous blood from an intact section of small intestine, filled with 5 per cent alcohol in water, contained as high as 25 milligrams of alcohol per cc. If Gettler will repeat his dog experiments and use peripheral venous blood taken immediately before the death of the animal, we believe he will find no discrepancy whatever between his results and ours.…”

Section: Blood Vs Brain (P 236) and Equilibrium And Concentration (mentioning

confidence: 99%

Medicolegal Aspects of Chemical Tests of Alcoholic Intoxication: Comments on Dr. I. M. Rabinowitch's Paper

Harger¹

1948

Journal of Criminal Law and Criminology (1931-1951)

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Circulatory Disturbances Caused by Intestinal Obstruction

Cited by 32 publications

References 0 publications

Effects of Distension and Acetylcholine on Intestinal Blood Flow <i>in vivo</i>

Effects of Distension and Acetylcholine on Intestinal Blood Flow <i>in vivo</i>

Management of colonic volvulus

Medicolegal Aspects of Chemical Tests of Alcoholic Intoxication: Comments on Dr. I. M. Rabinowitch's Paper

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