Circulating Red Cell Volume Measured Simultaneously by the Radioactive Iron and Dye Methods 1

Gibson, John G.; Peacock, Wendell C.; Seligman, Arnold M.; Sack, Theodore

doi:10.1172/jci101771

Cited by 132 publications

(58 citation statements)

References 27 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We wanted to determine a nomogram from which to predict the red blood cell, plasma and total blood volumes from body surface area and body weight. Red blood cell, plasma and total blood volumes were found to correlate with both body surface area (BSA) and body weight (BW), a finding similar to that reported by other investigators who studied younger subjects [1][2][3][4][5][6][7][8][9][10] . In our study, the regression equations were slightly more accurate for body surface area (BSA) than for body weight (BW).…”

supporting

confidence: 82%

Red Blood Cell Volume, Plasma Volume and Total Blood Volume in Healthy Elderly Men and Women Aged 64 to 100

Valeri¹,

Pivacek²,

Siebens³

et al. 1992

View full text Add to dashboard Cite

supporting

confidence: 82%

Red Blood Cell Volume, Plasma Volume and Total Blood Volume in Healthy Elderly Men and Women Aged 64 to 100

Valeri¹,

Pivacek²,

Siebens³

et al. 1992

View full text Add to dashboard Cite

“…If ratios proved constant over a large span of weight, a plot of blood volume against weight in a group of normal individuals would show points scattering about a line passing through the origin of the graph. But replotting of data from tables of "normal" adult blood volumes given in the literature11 [18][19][20][21][22][23][24] shows that least squares regression lines of blood volume on weight pass considerably above the origin. In figure 7, line A represents a constant ratio of 70 ml., Kg., whereas line B is an idealized line based on available data; it demonstrates that in heavy persons the ratio of blood volume to weight is smaller than in lighter individuals.…”

Section: Blood Volume Methodsmentioning

confidence: 99%

Change in Relationship of Blood Volume to Weight in Congestive Heart Failure

Funkhouser¹,

Pritchard²,

Littell³

1957

Circulation

View full text Add to dashboard Cite

Blood volume has been estimated in a small group of nonedematous hospitalized patients and in cardiac patients in severe congestive failure by both Cr 51 -labeled red cells and iodinated (I 131 ) human serum albumin. In the analysis of the data attention is directed to a fallacy inherent in the usual ratio method of relating blood volume to weight. An alternative method of analysis is proposed that not only yields greater accuracy, but makes the analysis more sensitive. The authors present their interpretation of the effects of tissue wasting and accumulation of edema fluid on the changes in the relationship between blood volume and weight in congestive heart failure. Analyzing other data from the literature by this method the authors have demonstrated a relationship between the amount of edema fluid and the increase in blood volume in congestive failure.

show abstract

“…Three samples were diluted immediately with 10 ml. of isotonic saline, then centrifuged as quickly as pos- (12). The total circulating red cell mass was calculated on the basis of the plasma volume and venous hematocrit, the latter having been modified by the correction factor 0.9 to correct for plasma occluded in the packed cell mass or for inequalities between the hematocrit of large and small vessels or for a combination of both.…”

mentioning

confidence: 99%

The Use of Radioactive Chromium 51 as an Erythrocyte Tagging Agent for the Determination of Red Cell Survival in Vivo 12

Ebaugh¹,

Emerson²,

Ross³

et al. 1953

J. Clin. Invest.

307

View full text Add to dashboard Cite

One of the most useful methods available for the quantitative measurement of hemolytic rates in clinical subjects and for the evaluation of red cell viability after storage is based on the survival of transfused erythrocytes. Access to such data, however, has been restricted because of limitations in the methods hithertofore available for measuring red cell survival in vivo.The differential agglutination method of counting donor cells, the procedure most commonly employed, has limitations in that large transfusions are required;* the donor blood must be devoid of all antigenic isoagglutinins which are not likewise possessed by the recipient; the recipient's cells must contain agglutinogen A or B or M or a combination of the three agglutinogens which is not contained in the donor blood; and, finally, this method excludes the use of autotransfusion, which would eliminate the risk of transmission of hemologous serum jaundice.The labelling of donor cells with radioactive iron (Fe55) permits the conduct of survival studies on a short term basis (1-3) but re-utilization of radioactive iron released from hemolyzed donor cells and the subsequent incorporation of this label in the recipient's red cells preclude its use in studies extending for periods longer than 24 to 48 hours.

show abstract

Circulating Red Cell Volume Measured Simultaneously by the Radioactive Iron and Dye Methods 1

Cited by 132 publications

References 27 publications

Red Blood Cell Volume, Plasma Volume and Total Blood Volume in Healthy Elderly Men and Women Aged 64 to 100

Red Blood Cell Volume, Plasma Volume and Total Blood Volume in Healthy Elderly Men and Women Aged 64 to 100

Change in Relationship of Blood Volume to Weight in Congestive Heart Failure

The Use of Radioactive Chromium 51 as an Erythrocyte Tagging Agent for the Determination of Red Cell Survival in Vivo 12

Contact Info

Product

Resources

About