Abstract:Background: One of the most orthopedic problems seen in the equine is osteoarthritis (OA). The present study tracks some biochemical, epigenetic, and transcriptomic factors along different stages of monoiodoacetate (MIA) induced OA in donkeys in serum and synovial fluid. The aim of the study was the detection of sensitive noninvasive early biomarkers.Methods: OA was induced by a single intra-articular injection of 25mg of MIA into the left radiocarpal joint of nine donkeys. Serum and synovial samples were take… Show more
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