Circulating markers of neutrophil activation and lung injury in pediatric pneumonia in low-resource settings

Konrad, Emily; Soo, Jeremy; Conroy, Andrea L.; Namasopo, Sophie; Opoka, Robert O.; Hawkes, Michael

doi:10.1080/20477724.2022.2160885

Cited by 2 publications

(1 citation statement)

References 44 publications

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“…However, in patients with elevated white blood cells, targeted specimen culture to determine the subsequent antibiotic treatment has clinical signi cance. The combination of quantitative biomarkers helps to safely stop antibiotics in patients with low possibility of bacterial infection [22].…”

Section: Antibioticmentioning

confidence: 99%

Influence of non-tuberculous bacterial infection on prognosis of hemoptysis

FAN,

CHANG,

WANG

2024

Preprint

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Objective Non-tuberculous bacterial infection delayed the prognosis and discharge time of patients with hemoptysis. This paper mainly analyzed the bacterial infection of lung and its mechanism. Methods Sixty-two patients with pulmonary hemoptysis accompanied by bacterial infection in the past 5 years were screened and divided into the experimental group and the control group according to whether leukocytes were elevated after bacterial infection. Multiple COX regression analysis was performed on gender, age, leukocytes, C-reactive protein, prothrombinase time and platelets of the two groups, and the correlation between PLT and PT and bacterial infection was analyzed by subject work characteristic curves. Results The decrease of PLT and the prolongation of PT were positively correlated with the hemoptysis caused by leukocyte elevation. Conclusion Patients with elevated white blood cells after bacterial infection can significantly prolong PT and decrease PLT. For patients with hemoptysis accompanied by bacterial infection, increasing PLT can play a dual role in hemostasis and control inflammation.

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Section: Antibioticmentioning

confidence: 99%

Influence of non-tuberculous bacterial infection on prognosis of hemoptysis

FAN,

CHANG,

WANG

2024

Preprint

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Location-based prediction model for Crohn’s disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies

Sipeki,

Kovats,

Deutschmann

et al. 2023

World J Gastroenterol

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Esophageal cancer (EC) has a high incidence and mortality rate and is emerging as one of the most common health problems globally. Owing to the lack of sensitive detection methods, uncontrollable rapid metastasis, and pervasive treatment resistance, EC is often diagnosed in advanced stages and is susceptible to local recurrence. Exosomes are important components of intercellular communication and the exosome-mediated crosstalk between the cancer and surrounding cells within the tumor microenvironment plays a crucial role in the metastasis, progression, and therapeutic resistance of EC. Considering the critical role of exosomes in tumor pathogenesis, this review focused on elucidating the impact of exosomes on EC metastasis and therapeutic resistance. Here, we summarized the relevant signaling pathways involved in these processes. In addition, we discussed the potential clinical applications of exosomes for the early diagnosis, prognosis, and treatment of EC.

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Circulating markers of neutrophil activation and lung injury in pediatric pneumonia in low-resource settings

Cited by 2 publications

References 44 publications

Influence of non-tuberculous bacterial infection on prognosis of hemoptysis

Influence of non-tuberculous bacterial infection on prognosis of hemoptysis

Location-based prediction model for Crohn’s disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies

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