2022
DOI: 10.1007/s12098-022-04084-5
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Circulating Histones and Severity of Illness in Children with Sepsis: A Prospective Observational Study

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Cited by 1 publication
(2 citation statements)
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“…There is a paucity of studies on the role of histones in critically ill children with sepsis. One of the first studies in this area conducted at a tertiary care hospital in India by Sidana et al warrants attention [4]. This prospective observational study aimed to measure circulating histone H3 levels in children with severe sepsis, and evaluate its role in the severity of illness and organ dysfunction.…”
Section: Declarationsmentioning
confidence: 99%
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“…There is a paucity of studies on the role of histones in critically ill children with sepsis. One of the first studies in this area conducted at a tertiary care hospital in India by Sidana et al warrants attention [4]. This prospective observational study aimed to measure circulating histone H3 levels in children with severe sepsis, and evaluate its role in the severity of illness and organ dysfunction.…”
Section: Declarationsmentioning
confidence: 99%
“…Association between high histone levels and thrombocytopenia has been shown in critically ill adult patients [6]. The study by Sidana et al also demonstrated higher H3 levels in patients with thrombocytopenia, though the difference was not statistically significant [4].…”
mentioning
confidence: 96%