Abstract:There have been numerous methods proposed to measure the circulating blood volume (CBV). Nevertheless, none of them have been massively and routinely accepted in clinical diagnosis. This study describes a simple and rapid method, on a rabbit model, using the dilution of autologous red cells labeled with a nitroxide radical (Iodoacetamide-TEMPO), which can be detected by electronic spin resonance (ESR) spectroscopy. Blood samples were withdrawn and re-injected using the ears' marginal veins. The average CBV mea… Show more
“…The "historical" one is based on the nitroxide moiety excluding the unsaturated linked spin labels as Tempo or Tempol [11][12][13][14][15][16][17][18][19]. The second family of radicals is an emerging one, based on the verdazyl moiety.…”
Section: Description and Stability Of The Organic Radicalsmentioning
“…The "historical" one is based on the nitroxide moiety excluding the unsaturated linked spin labels as Tempo or Tempol [11][12][13][14][15][16][17][18][19]. The second family of radicals is an emerging one, based on the verdazyl moiety.…”
Section: Description and Stability Of The Organic Radicalsmentioning
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