Circulating Antibodies in Reticuloses

Reticuloendothelial System Phagocytic Function in Patients with Hodgkin's Disease*

“…Certain of these may occur throughout the patient's course and are possibly related to deficient mechanisms of delayed hypersensitivity (3)(4)(5)(6). However, the majority of infectious episodes occur late in the course of the illness (2), when other factors, such as the extensive use of immunosuppressive agents, especially corticosteroids (2), lymphocytopenia (7), and alterations in circulating antibody (8)(9)(10), may be implicated.…”

Measurements of Protein Synthesis by Lymphocytes <i>in vitro </i>in Diseases of the Lymphoid Tissues

“…The low total protein synthesis by the circulating lymphocytes in lymphoma, lymphosarcoma and macroglobulinaemia seems to be related to the poor immunological function reported in these so-called lymphoproliférative disorders [3,4,10,17].…”

“…Diagnosis of chronic lymphatic leukaemia (CLL) was made on a blood count of more than 9,000 lymphocytes/mm3 and the finding of a non-follicular lymphocytic infiltra tion of the bone marrow [3]. Multiple myeloma was diagnosed by a y-or /?-'M' band of paraprotein on serum electrophoresis which was not precipitated from the serum by rivanol [15] associated with an infiltration of the bone marrow by plasma cells.…”

Serological and Morphological Studies on Progressive Multifocal Leucoencephalopathy Virus

“…Antibody against PML virus had not been detected previously in sera obtained from PML-patients [7,8]. This was understandable since PML usually occurred after a history of a long-standing disease such as Hodgkin's disease or chronic lymphatic leukemia, in which the immunological responses were depressed [3,9]. Immunoagglutination technique using the electron microscope (micro-agglutination) is useful in detecting antibody against viruses and to analyze the antigenic characteristics using small quantities of antigens and antisera [1,2,5].…”