Circular RNA_015343 sponges microRNA‐25 to regulate viability, proliferation, and milk fat synthesis of ovine mammary epithelial cells via INSIG1
Xinmiao Wu,
Jiqing Wang,
Zhiyun Hao
et al.
Abstract:In our previous study, circ_015343 was found to inhibit the viability and proliferation of ovine mammary epithelial cells (OMECs) and the expression levels of milk fat synthesis marker genes, but the regulatory mechanism underlying the processes is still unclear. Accordingly in this study, the target relationships between circ_015343 with miR‐25 and between miR‐25 with insulin induced gene 1 (INSIG1) were verified, and the functions of miR‐25 and INSIG1 were investigated in OMECs. The dual‐luciferase reporter … Show more
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