Circular dichroism of L-tryptophan by an improved dichrograph

Myer, Yash P.; MacDonald, Lawrence H.

doi:10.1021/ja01002a071

Cited by 52 publications

(13 citation statements)

References 1 publication

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“…The assignment of CD bands to Trp is further supported by comparison with spectra of monomeric [8] and polymeric Trp [9] and certain proteins such as . 2).…”

Section: Comparative Attributionmentioning

confidence: 88%

Tryptophanyl circular dichroism in a special hemoglobin

Wollmer

Buse

1971

FEBS Letters

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“…The assignment of CD bands to Trp is further supported by comparison with spectra of monomeric [8] and polymeric Trp [9] and certain proteins such as . 2).…”

Section: Comparative Attributionmentioning

confidence: 88%

Tryptophanyl circular dichroism in a special hemoglobin

Wollmer

Buse

1971

FEBS Letters

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“…I n the 190-240 mp region two other strong bands (196 and 218 mp) are also v i~i b l e .~~,~~ The CD spectrum of this amino acid, which contains the indole chromophore, was recently shown to present three Cotton effects around 280 mp reflecting the isotropic absorption bands of this compound. 33 Below 240 mp only two of the four C D bands reflect their counterpart in the UV spectrum.…”

Section: A Uv and CD Spectra Of Amino Acids Containing Aromatic Sidementioning

confidence: 99%

Conformational studies of proteins with aromatic side‐chain effects

Goodman¹,

Toniolo²

1968

Biopolymers

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SynopsisWe present here a brief analysis of ultraviolet isotropic absorption and related circular dichroism of the n-r* and T-T* transitions for the peptide (amide) chromophore in the 185-240 mp region. Investigations by ultraviolet absorption and circular dichroism techniques on natural amino acids with aromatic chromophores in their side chains are also reported. By taking into account both the peptide and aromatic transitions we discuss the conformational studies of proteins with aromatic side-chain effects. Our attention is largely focused on the optical rotatory dispersion and circular dichroism spectra of these proteins in the near ultraviolet region, where characteristic aromatic side-chain bands occur. The 185-240 mp region is also discussed when evidence exists of overlapping Cotton effects of aromatic and peptide groups.

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“…The sign of this CD band is the same for all aliphatic L-amino acids. It is not the case for tryptophan [37], whose indole chromophore exhibits a strong CD band centered at about 195 nm, with the opposite sign to the carboxyl 210 nm band. Proline also has a strong CD band of opposite sign around 193 nm in a neutral solution.…”

Section: Origins Of Extraterrestrial Non-racemic Organic Mattermentioning

confidence: 91%

Biological Homochirality on the Earth, or in the Universe? A Selective Review

Davankov

2018

Symmetry

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The discovery of meteoritic alpha-amino acids with significant enantiomeric excesses of the L-form has suggested that some cosmic factors could serve as the initial source for chiral imbalance of organic compounds delivered to the early Earth. The paper reviews major hypothesis considering the influence of chiral irradiation and chiral combinations of physical fields on the possible ways asymmetric synthesis and transformations of organics could take place within the solar system. They could result in a small enantiomeric imbalance of some groups of compounds. More attention is paid to the hypothesis on parity violation of weak interaction that was supposed to cause homochirality of all primary particles and a more significant homochirality of compounds directly synthesized from the latter in a plasma reactor. The first experiment with material synthesized in a plasma torch resulting from a super-high-velocity impact showed formation of alanine with the excess of L-form between 7 and 25%. The supposed conclusion is that L-amino acids could serve as a starting homochiral biomolecular pool for life to emerge all over the Universe.

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Circular dichroism of L-tryptophan by an improved dichrograph

Cited by 52 publications

References 1 publication

Tryptophanyl circular dichroism in a special hemoglobin

Tryptophanyl circular dichroism in a special hemoglobin

Conformational studies of proteins with aromatic side‐chain effects

Biological Homochirality on the Earth, or in the Universe? A Selective Review

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