2021
DOI: 10.1111/cpr.13047
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CircSLC7A2 protects against osteoarthritis through inhibition of the miR‐4498/TIMP3 axis

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Cited by 26 publications
(10 citation statements)
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“…A previous study showed that the RNA-binding protein FUS can affect circular RNA expression [45][46][47] . Our study could be improved by evaluating the upstream mechanisms of the circFNDC3B/miR-525-5p/HO-1 axis.…”
Section: Discussionmentioning
confidence: 99%
“…A previous study showed that the RNA-binding protein FUS can affect circular RNA expression [45][46][47] . Our study could be improved by evaluating the upstream mechanisms of the circFNDC3B/miR-525-5p/HO-1 axis.…”
Section: Discussionmentioning
confidence: 99%
“…Circular RNAs (CircRNAs), covalently closed endogenous RNAs, are noncoding RNAs characterized by a covalent loop configuration without 5′ end caps or 3′ poly(A) tails ( Ni et al, 2021 ). Furthermore, circRNAs are involved in the pathophysiological process of various diseases, such as diabetes mellitus, neurological disorders, cardiovascular diseases, skeletal muscle disease, and cancer ( Kristensen et al, 2019 ).…”
Section: The Treatments With Hif-1 In Osteoarthritismentioning
confidence: 99%
“…In recent times, RBPs have also been reported to participate in the splicing and formation of circRNAs. Ni and others reported that FUS binds to the GUGGU sequences at nt 358 and 409 proximal to the back-splicing sites (exon 8) and one sequence at nt 499 proximal to the back-splicing sites (exon 10) of SLC7A2 to induce circSLC7A2 formation ( Ni et al, 2021 ).…”
Section: Rna-binding Proteins In Regulating Rna Metabolismmentioning
confidence: 99%