circRNA-miRNA-mRNA networks reveal a proangiogenic action of circNPHP1 in human ischemic heart disease
Maryam Anwar,
Moumita Sarkar,
Kerrie Ford
et al.
Abstract:BackgroundIschemic heart disease (IHD) is characterized by insufficient myocardial blood flow and aggravated by diabetes. IHD is often treated by coronary revascularization. Complementary therapies that increase the microvascular flow by promoting endothelial homeostasis and repair are still lacking and require the identification of new therapeutic targets. The expression of protein coding genes is regulated by multimodal interactions between different classes of non-coding RNAs. This study aimed to 1) unravel… Show more
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