Circadian Sleep‐Waking Rhythm Disturbance in Blind Adolescence

Visual Impairment and Circadian Rhythm Sleep Disorders

“…47 Additionally, 40% of subjects recognized that the symptoms were cyclic or episodic, an important characteristic of circadian rhythm sleep disorders (see below). Sasaki et al 48 demonstrated a lower Incidence of sleep-wake complaints (40%) in 73 blind teenagers, although they did postulate that an Increase in sleep disorder (delayed sleep phase syndrome and non-24-h sleepwake rhythm) was associated with a decrease in light perception. More recently, Léger et al 49 reported on the results of a postal study In ~ 800 blind Individuals, who were age, sex - and location-matched with sighted controls.…”

Circadian activity–rest and sleep–wake rhythms in blind adolescents and adults

“…In the presence of other time indicators such as social cues, circadian abnormalities do not prevent blind people from adapting to a 24-hour schedule, though they often complain of sleep difficulties (Tzischinsky et al 1991;Sack and Lewy 1992;Sasaki et al 1992).…”

Melatonin treatment of sleep–wake cycle disorders in children and adolescents

“…The abnormal endogenous MLT secretion in blind children with sleep-wake cycle disorders was an important finding 136 . Sasaki in 1992 137 showed that in children with diminishing vision the prevalence of sleep-wake-rhythm disorders tends to increase. Similar findings have been noted in adults 139 .…”