Circadian rhythm of wrist temperature in normal-living subjects

Sarabia, J.A.; Rol, María Ángeles; Mendiola, P.; Madrid, Juan Antonio

doi:10.1016/j.physbeh.2008.08.005

Cited by 196 publications

(233 citation statements)

References 43 publications

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“…Distal skin temperature is driven by the central pacemaker (Bonmati-Carrion et al 2014;Kräuchi et al 2005;Kräuchi et al 2006;Martinez-Nicolas et al 2013Sarabia et al 2008) showing a strong endogenous component after mathematical demasking or under constant routine protocol (Krauchi and WirzJustice 1994; Kräuchi et al 2006;Martinez-Nicolas et al 2013), although as occurs with core body temperature, melatonin, or sleep rhythms, it is masked by external factors such as activity, sleep, light, environmental temperature, or body position (Cajochen et al Besides, DST reflects the endogenous rhythm of sympathetic-parasympathetic activation on vessel lumen diameter, in relation to day activity and night rest, respectively (Charkoudian 2003).…”

Section: Discussionmentioning

confidence: 99%

Ontogeny and aging of the distal skin temperature rhythm in humans

Batinga

Martínez-Nicolás

Zornoza-Moreno

et al. 2015

AGE

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In circadian terms, human ontogeny is characterized by the emergence of a daily pattern, from a previous ultradian pattern, for most variables during the first 6 months of life. Circadian aging in humans is characterized by a phase advance, accompanied by rhythm fragmentation and flattening. Despite an expanding body of literature focused on distal skin temperature, little information is available about the ontogeny and practically nothing about age-related changes in this rhythm. Thus, the aim was to evaluate the degree of maturation and aging of the circadian pattern of distal skin temperature to identify those parameters that are modified throughout life and could be used to differentiate subjects according to their age. For this, distal skin temperature was measured in 197 volunteers (55 % women), including babies aged 15 days (30 subjects), 1 month (28 subjects), 3 months (31 subjects), and 6 months (10 subjects); young adults aged 19 years (37 subjects); middle-aged persons aged 46 years (27 subjects); older people aged 72 (34 subjects). Circadian system maturation was associated with an increase in amplitude and a reduction in skin temperature during sleep. During adulthood, women showed a more robust pattern (lower fragmentation, and higher night-time temperature, amplitude, circadian function index, and first harmonic relative power); however, these differences were lost with aging, a period of life that was consistently associated with a phase advance of the rhythm. In summary, distal skin temperature pattern can be used as a robust variable to discern between different ages throughout the life.

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Section: Discussionmentioning

confidence: 99%

Ontogeny and aging of the distal skin temperature rhythm in humans

Batinga

Martínez-Nicolás

Zornoza-Moreno

et al. 2015

AGE

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“…There is also a secondary peak around afternoon, a period associated with naps, after their usual lunch time, and a dip between 2000 and 2200 hours, a period already known as the 'wake maintenance zone'. 17 In general, a 'healthy circadian pattern' includes the following: high amplitude, high regularity (high IS) and low fragmentation (low IV). 17 In the current work, wrist-temperature IV was also related to the effectiveness of the intervention, suggesting a greater fragmentation of the rhythm in low responders as compared with high responders.…”

Section: Discussionmentioning

confidence: 99%

“…17 In general, a 'healthy circadian pattern' includes the following: high amplitude, high regularity (high IS) and low fragmentation (low IV). 17 In the current work, wrist-temperature IV was also related to the effectiveness of the intervention, suggesting a greater fragmentation of the rhythm in low responders as compared with high responders. IV is a measure of fragmentation of the rhythm that seems to be dependent on endogenous circadian disturbances, as it shows a low correlation with functional, social and emotional well being.…”

Section: Discussionmentioning

confidence: 99%

“…This has been evaluated for different ages [13][14][15][16] and pathologies. 17 Recently, it has been published that peripheral body temperature measured at the wrist (herein after called wrist temperature) rhythm exhibits a strong endogenous component, despite the existence of multiple external influences, and it has been proposed that it could be considered a valuable and minimally invasive measure to assess circadian physiology under ambulatory conditions. 18 Moreover, a recent study has demonstrated that wrist-temperature phase indexes are capable of accurately detecting the phase of the circadian system in subjects recorded under normal living conditions as compare with Dim Light Melatonin onset.…”

Section: Introductionmentioning

confidence: 99%

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Circadian rhythmicity as a predictor of weight-loss effectiveness

et al. 2013

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“…A literature search yields numerous examples of the use of iButtons for applications relevant to the pharmaceutical industry, including monitoring of human subjects [4,5] and cold-chain transport applications [6]. However, to date, there does not appear to be any demonstration of iButtons®/ Pyrobuttons for monitoring pharmaceutical processes.…”

Section: Introductionmentioning

confidence: 99%

Use of Commercial Data Loggers to Develop Process Understanding in Pharmaceutical Unit Operations

2010

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Due to the growing emphasis on quality by design during pharmaceutical development, accurate process data collection has become even more crucial. While process analytical technology has emphasized complex spectroscopic techniques, univariate measurements can provide data to develop further process understanding, such as assessing the impact of operating conditions on downstream product attributes or spatially mapping the equipment environment for building detailed process models. Since pharmaceutical scientists have historically had little ability to influence equipment manufacturers on the number, type, or location of sensors intended to measure processing conditions, additional univariate measurements have been obtained using robust temperature/humidity sensors in a number of unit operations. The small size of the sensors allows them to be placed anywhere they are not subject to mechanical damage, while the 21-CFR-11-compliant database provides for traceability for regulatory submissions. This work presents data from fixed-location and portable sensors for two widely used pieces of pharmaceutical equipment, film coaters and fluid bed systems. Portable sensors are also demonstrated as a viable means to obtain process data not available by fixed-location sensors, such as the tablet bed of a film coater. These sensors have been used for a range of process scales, from early-stage products with minimal drug substance to commercial-scale production.

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Circadian rhythm of wrist temperature in normal-living subjects

Cited by 196 publications

References 43 publications

Ontogeny and aging of the distal skin temperature rhythm in humans

Ontogeny and aging of the distal skin temperature rhythm in humans

Circadian rhythmicity as a predictor of weight-loss effectiveness

Use of Commercial Data Loggers to Develop Process Understanding in Pharmaceutical Unit Operations

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