1971
DOI: 10.1080/09291017109359272
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Circadian rhythm in the blind

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Cited by 15 publications
(10 citation statements)
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“…Taken together, the ipRGC non-visual pathway (sensitive particularly to blue light) seems to serve as a crucial role in the entrainment of the circadian rhythm (Legates, Fernandez, and Hattar 2014). This concept dates back to Hollwich's original postulation about the existence of a non-visual pathway involved in the synchronisation of the circadian rhythm (Hollwich and Dieckhues 1971).…”
Section: Discussionmentioning
confidence: 98%
“…Taken together, the ipRGC non-visual pathway (sensitive particularly to blue light) seems to serve as a crucial role in the entrainment of the circadian rhythm (Legates, Fernandez, and Hattar 2014). This concept dates back to Hollwich's original postulation about the existence of a non-visual pathway involved in the synchronisation of the circadian rhythm (Hollwich and Dieckhues 1971).…”
Section: Discussionmentioning
confidence: 98%
“…32 They found abnormalities in a wide variety of biochemical measurements In totally blind subjects (n=220) compared with those with severely Impaired vision (n=140) and sighted subjects (n=50). These changes Included reduced serum levels of glucose, protein, Cortisol, sodium, and raised levels of creatinine and potassium which were mirrored In urinary analysis.…”
Section: The Effect Of Visual Impairment On Circadian Entrainmentmentioning
confidence: 97%
“…Abnormal hormonal patterns have been reported in some visually Impaired patients for more than five decades. In the 1940s, Remler recognized that some blind patients had normal 24-hour rhythms whereas some had Inverted rhythms In rectal temperature, heart rate, blood pressure, and urinary excretion (1948 31 cited In Hollwich and Dleckhues 32 ). Subsequently, Orth and Island, 33 Kreiger and Rizzo, 34 Bodenheimer et al, 35 and D'Allessandro et al 36 all found Irregularities In the plasma profiles of corticosteroid production In a majority of blind subjects.…”
Section: The Effect Of Visual Impairment On Circadian Entrainmentmentioning
confidence: 99%
“…It is notable that the prevalence of “legal” blindness increases sharply with age, and that approximately half of all the blind people are 65 years of age or older 195 . This information appears most relevant to sleep disorders and biologic rhythm dysfunction, in view of evidence that sleep disorders are very common and significantly incapacitating in the blind community 186 and that blind people have abnormalities in their circadian rhythms 60,134,156,168,174,185,204,248 …”
Section: Biologic Rhythms and Sleep/wake Function In The Agedmentioning
confidence: 99%