Circadian Regulation of the Lactate Metabolic Kinetics in Mice Using the [1H-13C]-NMR Technique
Lili Chen,
Kefan Wu,
Jingang He
et al.
Abstract:Lactate is not only the energy substrate of neural cells, but also an important signal molecule in brain. In modern societies, disturbed circadian rhythms pose a global challenge. Therefore, exploring the in uence of circadian period on lactate and its metabolic kinetics is essential for the advancement of neuroscienti c research. In the present study, mice were infused [3-13 C] lactate through the tail vein for a duration of two minutes. After 30 minutes lactate metabolism, the animals were sacri ced and the … Show more
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