Circadian rapid eye movement sleep expression is associated with brain microstructural integrity in older adults
Michele Deantoni,
Mathilde Reyt,
Marine Dourte
et al.
Abstract:Rapid eye movement sleep (REMS) is increasingly suggested as a discriminant sleep state for subtle signs of age-related neurodegeneration. While REMS expression is under strong circadian control and circadian dysregulation increases with age, the association between brain aging and circadian REMS regulation has not yet been assessed. Here, we measure the circadian amplitude of REMS through a 40-h in-lab multiple nap protocol in controlled laboratory conditions, and brain microstructural integrity with quantita… Show more
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