Ciprofloxacin in the treatment of Mycobacterium fortuitum infection of the peroneal tendons. A case report

Abstract

In the case reported, M. fortuitum was sensitive in vitro to amikacin, erythromycin, tobramycin, and ciprofloxacin. Because the patient did not respond to long-term therapy with amikacin and erythromycin, an experimental antibiotic, ciprofloxacin, was tried. Only after extensive surgical debridement and 2 1/2 months of oral ciprofloxacin therapy was the infection eradicated and wound healing obtained. The authors conclude that a wound that has reopened, but remains indolent, exudes a clear, serous drainage and responds poorly to antibiotics should suggest a possible mycobacterial infection. Combination antibiotic therapy is recommended because of the high rate of relapse and development of resistance to drugs. Extensive surgical debridement of all infected tissue remains the primary treatment. The therapeutic value of ciprofloxacin and other newer antibiotics in the treatment of mycobacterial infection is promising.

Peroneal Tendon Reconstruction and Coverage for Treatment of Septic Peroneal Tenosynovitis: A Devastating Complication of Lateral Ankle Ligament Reconstruction With a Tendon Allograft

“…Septic peroneal tenosynovitis is even rarer and appears to have the potential for significant morbidity (1)(2)(3)(4)(5). Septic tenosynovitis has typically been more prevalent in the flexor tendons of the upper extremity (18).…”

“…Septic peroneal tenosynovitis is a rarely reported occurrence in medical studies (1)(2)(3)(4)(5). Various techniques for peroneal tendon reconstruction for the treatment of irreparable tears and rupture have been reported (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16).…”

“…All of these cases resolved with tenosynovectomy and pathogendirected pharmacotherapy. None of the cases resulted in significant loss of the peroneal tendons requiring reconstruction (1)(2)(3)(4)(5).…”