Ciprofloxacin and Norfloxacin Hybrid Compounds: Potential Anticancer
Agents
Sijongesonke Peter,
Blessing A. Aderibigbe
Abstract:Background::
The concept of utilizing drug repurposing/repositioning in the development
of hybrid molecules is an important strategy in drug discovery. Fluoroquinolones, a class of
antibiotics, have been reported to exhibit anticancer activities. Although anticancer drug development
is achieving some positive outcomes, there is still a need to develop new and effective anticancer
drugs. Some limitations associated with most of the available anticancer drugs are drug resistance
and toxicity, poor bio-distributi… Show more
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