Cinnamon supplementation improves menstrual cyclicity in women with polycystic ovary syndrome

Kort, Daniel H.; Sullivan, C.; Kostolias, A.; DePinho, J.; Løbo, Rogerio A.

doi:10.1016/j.fertnstert.2013.07.814

Cited by 2 publications

(4 citation statements)

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“…Only two RCTs analyzed showed changes in regularity of menstruation. 9,10 Characteristics of included studies The characteristics of included studies are described in Table 1. Two studies focused on Iranian women, 5,11 two others on Caucasian women from Columbia 9,10 and the last focused on New York, USA.…”

Section: Flow Chart Of Study Selectionmentioning

confidence: 99%

“…Only three studies made a specific range of body mass index (BMI) criteria for enrolling the patient in the study. 5,10,11 The mean age for each group was reported in each study, but not for one study 9 (mean age for all groups was 31.1 AE 2 years old). The mean age in each group reported by Hajimonfarednejad et al, 5 5,10,11 The dose of cinnamon given for intervention in four studies was the same (1500 mg cinnamon daily).…”

Section: Flow Chart Of Study Selectionmentioning

confidence: 99%

“…10 The results were the same in the Kort et al study, who concluded that there were significant changes in menstrual cyclicity after 24 weeks (p = 0.047). 9 In this meta-analysis, we analyze mean difference of post intervention menstrual cyclicity between the cinnamon and control groups. There was a significant difference between menstrual cyclicity post intervention in the cinnamon group and control group (2.28[1.83, 2.73]; p < 0.00001) (Figure 4K).…”

Section: Menstrual Cyclicitymentioning

confidence: 99%

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Cinnamon extract effects on insulin resistance, metabolic factors, and menstrual cyclicity of women with polycystic ovary syndrome: A systematic review and meta-analysis

Wahyuningtyas

Sa’adi

2021

F1000Res

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Background: Cinnamon is a herbal medicine that is supposed to improve the metabolic disorder polycystic ovary syndrome (PCOS), but there is still no data about the effectiveness and efficacy of this herbal medicine for the metabolic parameters of PCOS. This study aims to systematically evaluate the effects of cinnamon extract on improving insulin resistance, lipid profile and regularity of menstruation in PCOS women. Methods: This is a systematic review and meta-analysis of randomized controlled trials (RCTs) studies. We searched the MEDLINE, Cochrane, Google Scholar, and PubMed databases to identify relevant studies using cinnamon extract effects on insulin resistance, metabolic factors, and menstrual cyclicity of PCOS women. Results: Five RCTs consisting of 206 women were included in the meta-analysis. Significant differences were found in fasting blood glucose (FBG) (mean difference (MD)= -4.8 mg/dL, 95% CI: -8.04 to -1.57, p=0.004; 143 participants), High-Density Lipoprotein (HDL-cholesterol, HDL-C) (MD= -27.24 mg/dL, 95% CI: -32.62 to -21.85, p< 0.00001; 143 participants, Insulin level (MD = -2.20 mIU/dL, 95% CI: -4.17 to -0.23, p=0.03; 143 participants), and menstrual cyclicity in six months (MD= 2.28, 95% CI: 1.83 to 2.73, p< 0.00001; 33 participants) were obtained. Conclusion: Cinnamon can be a potential supplementary therapy agent for PCOS women as it improves fasting blood glucose, insulin level, HDL–cholesterol and menstrual cyclicity in PCOS women.

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Section: Flow Chart Of Study Selectionmentioning

confidence: 99%

Section: Flow Chart Of Study Selectionmentioning

confidence: 99%

Section: Menstrual Cyclicitymentioning

confidence: 99%

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Cinnamon extract effects on insulin resistance, metabolic factors, and menstrual cyclicity of women with polycystic ovary syndrome: A systematic review and meta-analysis

Wahyuningtyas

Sa’adi

2021

F1000Res

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“…A retrospective study found that women who consume greater amounts of dairy (high and low fat) in adolescence may halt the progression of endometriosis and also reduce pain symptoms in adulthood [26]. For women with PCOS, adding cinnamon supplements to their diet may increase menstrual cycle regularity [27].…”

Section: Diet: Including Supplementsmentioning

confidence: 99%