Cinetique d'amination de la cyclohexene-2 one-1

Catalysis of the reversible elimination reactions of substituted N-(.beta.-phenylethyl)quinuclidinium ions in aqueous solution

“…The value of ß 10 is larger than the values of 0.43 and 0.56 for the addition of amines to acrylo-nitrile18 and methyl vinyl ketone,19 respectively, and the small values that are suggested by the rate constants for addition of amines to phenyl vinyl sulfone21 and cyclohexen-2-one. 22 The complementary result is found in the elimination direction, for which an early transition state for leaving-group expulsion is indicated by the small dependence of the rate on the pA' of the leaving quinuclidine (Figure 3). The same values of /3]g = -0.18 are found for the reactions catalyzed by hydroxide ion (closed circles) and by quinuclidine (open circles).…”