Cineangiocardiographic Recordings of the Cyclic Changes in Volume of the Left Ventricle

Gribbe, P.; Hirvonen, L; Lind, John; Wegelius, C

doi:10.1159/000166431

Cited by 88 publications

(18 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…reported by Chapman and associates 10 ' u using a cineangiographic technic in the anesthetized dog. The values reported by Gribbe and co-workers, 12 who also used cineangiography, are much smaller since the maximal end-systolic volume shown in those studies on dogs weighing 8 to 15 Kg. was approximately 10 ml.…”

mentioning

confidence: 77%

Ventricular Nonmixing as a Source of Error in the Estimation of Ventricular Volume by the Indicator-Dilution Technic

Swan

Beck

1960

Circulation Research

View full text Add to dashboard Cite

1. In the anesthetized dog, end-diastolic, end-systolic and stroke volumes for the left ventricle have been calculated according to the method of Holt from dilution curves recorded at the aortic root. For heart rates of less than 120 beats per minute, the catheterdensitometer systems used gave 90 to 95 per cent of the true concentration in the aortic root at the end of diastole. 2. Average volumes of 2.96, 1.63 and 1.33 ml./Kg. of body weight were calculated for each of these parameters. The interindividual and intraindividual variations about these means amounted to ± 30 to 50 per cent. 3. In approximately 15 per cent of the dilution curves the concentration of dye in the aortic root during early systole (phase of maximal ejection) showed a transient, markedly low value compared with that of the end of diastole. This can be explained only on the basis of the preferential ejection from the heart in early systole of the undyed, newly entering blood from the left atrium, which had mixed poorly with the residual volume of the ventricle. Qualitative inspection of cineangiograms confirmed this impression and demonstrated that a residuum of contrast medium failed to mix with the incoming blood from the left atrium. 4. In addition, there is evidence for the possibility of overestiination of stroke volumes from dilution curves recorded immediately proximal to the injection chamber. 5. Incomplete mixing of the left artial blood with the residual volume of the ventricle precludes accurate quantitation of the changes of volume in the ventricle by the simple formulas proposed by previous authors. This phenomenon may serve to explain the considerable variability that is found in the present study and in the literature.

show abstract

mentioning

confidence: 77%

Ventricular Nonmixing as a Source of Error in the Estimation of Ventricular Volume by the Indicator-Dilution Technic

Swan

Beck

1960

Circulation Research

View full text Add to dashboard Cite

show abstract

“…They can be compared with results from experiments with mechanical emptying of the ventricles and establishment of the ventricular volume in the state of elastic equilibrium [ Table 2 (14,16)]. Results presented by Kolder and associates (3) indicate that the variation with temperature of the ventricular volume of the quiescent heart in the state of elastic equilibrium is within the measurement error of the technique used.…”

Section: Discussionmentioning

confidence: 99%

Ventricular Volume of Nonbeating Excised Dog Hearts in the State of Elastic Equilibrium

Brecher

Kolder

Horres

1966

Circulation Research

View full text Add to dashboard Cite

The volume in the left ventricle and that in the right ventricle were measured statically starting from zero transmural pressure, when the ventricle is in the state of elastic equilibrium, to a negative transmural pressure of 30 mm Hg. Freshly excised dog hearts were submerged in Ringer's solution at 10°C to establish zero transmural pressure, to offset the contribution of the weight of the ventricular walls on the shape of the ventricle, and to retard the onset of postmortem changes. The volume was approximated by an equation which included a power function of the body weight and another of the ventricular weight. For male dogs, the left ventricle when in the state of elastic equilibrium contained a mean volume of 14.5 ml for a body weight of 10 kg and a ventricular weight of 58 g; the corresponding figure for the right ventricle was 12.2 ml. In a quiescent heart below a certain ventricular volume, potential energy will be stored in structural elements of the ventricle wall that will facilitate the filling of the ventricle. This work was supported in part by the Life Insurance Medical Research Fund, by Grant H-3796 from the National Institutes of Health, U. S. Public Health Service, and by the Georgia Heart Association. ADDITIONAL KEY WORDSPreliminary results were presented as "Form Elasticity of the Heart," at the Fall Meeting of the American Physiological Society, Stanford, California, 1960. Accepted for publication October 17, 1986. the ventricular volume in the state of elastic equilibrium, could store potential energy in the strained elastic elements. Diastolic recoil would then tend to produce a negative transmural pressure of the ventricle, increase the atrioventricular pressure difference, and facilitate the filling of the ventricle through a "vis a fronte," i.e. suction. A graphic representation of the concept was previously published by Kolder et al. (3). The purpose of the present study is to measure under controlled conditions the left and right ventricular volume in the state of elastic equilibrium and to relate the measured volumes to body weight, weight of both ventricles, and sex. This statistical information will be of value in assessing the ventricular volume at which elastic forces in the ventricular wall start contributing to diastolic filling. MethodThe technique used for the present experiments is similar to that previously described (3). Dogs were anesthetized with pentobarbital (30 mg/kg body weight, iv) and rapidly exsanguinated. The chest was opened and the heart removed

show abstract

“…Burch, Ray, and Cronvich suggested the sphere for this purpose (11). Others have proposed from angiographic study that the left ventricle be represented as an ellipsoid (2,3,12). Ventricular wall forces, stresses, and circumferential shortening will vary with curvature in a nonspherical chamber.…”

Section: Methodsmentioning

confidence: 99%

Left Ventricular Volume in Man Measured by Thermodilution*

Gorlin¹,

Rolett²,

Yurchak³

et al. 1964

J. Clin. Invest.

110

View full text Add to dashboard Cite

The most important contributions to the quantification of left ventricular volume in man to date have employed the angiographic technic (1-3). Although stated to be accurate, this method is time-consuming, requires expensive equipment, alters ventricular contraction, is relatively limited in the number of observations that can be made safely, and may present the hazard of myocardial injury. The indicator dilution method for estimation of ventricular volume (4, 5), on the other hand, although more dependent on uniform ventricular mixing and totally unrevealing of ventricular shape, presents the advantages of having little effect on the heart, unlimited repeatability, and simplicity of calculation. This communication reports measurement of left ventricular volume in man by the thermodilution technic (6) under a variety of conditions and the utilization of these data to determine ventricular systolic force and fiber shortening. MethodsThirty-nine patients were studied and classified on the basis of clinical evidence and diagnostic cardiac catheterization. Subjects with mitral regurgitation and significant aortic regurgitation were not included because of the inability to calculate true left ventricular volume in the presence of these defects (7). The following categories were studied:"Normal" left ventricle (22 subjects). This category was divided into groups A and B according to the apparent degree of "normality." Group A comprised seven

show abstract

Cineangiocardiographic Recordings of the Cyclic Changes in Volume of the Left Ventricle

Cited by 88 publications

References 4 publications

Ventricular Nonmixing as a Source of Error in the Estimation of Ventricular Volume by the Indicator-Dilution Technic

Ventricular Nonmixing as a Source of Error in the Estimation of Ventricular Volume by the Indicator-Dilution Technic

Ventricular Volume of Nonbeating Excised Dog Hearts in the State of Elastic Equilibrium

Left Ventricular Volume in Man Measured by Thermodilution*

Contact Info

Product

Resources

About