Cine MR CSF Flow Study in Hydrocephalus: What are the Valuable Parameters?

Kim, M H; Shin, Kyu Man; Song, Jooeun

doi:10.1007/978-3-7091-6475-4_99

Cited by 13 publications

(9 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With respect to prognostic MRI studies, numerous studies have investigated the association between aqueductal pulsatility and outcome from shunting [50,54,61,62,67,159,161,163,167,179,180]. The first example of a prognostic, MRI-based flow pulsatility measure is the stroke volume measure; Bradley et al indicated favorable outcome for patients with aqueductal stroke volumes above 42 μl [50].…”

Section: The Intracranial Pulse Wave - Clinical Studiesmentioning

confidence: 99%

The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility

Wagshul

Eide

Madsen

2011

Fluids Barriers CNS

386

311

View full text Add to dashboard Cite

The maintenance of adequate blood flow to the brain is critical for normal brain function; cerebral blood flow, its regulation and the effect of alteration in this flow with disease have been studied extensively and are very well understood. This flow is not steady, however; the systolic increase in blood pressure over the cardiac cycle causes regular variations in blood flow into and throughout the brain that are synchronous with the heart beat. Because the brain is contained within the fixed skull, these pulsations in flow and pressure are in turn transferred into brain tissue and all of the fluids contained therein including cerebrospinal fluid. While intracranial pulsatility has not been a primary focus of the clinical community, considerable data have accrued over the last sixty years and new applications are emerging to this day. Investigators have found it a useful marker in certain diseases, particularly in hydrocephalus and traumatic brain injury where large changes in intracranial pressure and in the biomechanical properties of the brain can lead to significant changes in pressure and flow pulsatility. In this work, we review the history of intracranial pulsatility beginning with its discovery and early characterization, consider the specific technologies such as transcranial Doppler and phase contrast MRI used to assess various aspects of brain pulsations, and examine the experimental and clinical studies which have used pulsatility to better understand brain function in health and with disease.

show abstract

Section: The Intracranial Pulse Wave - Clinical Studiesmentioning

confidence: 99%

The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility

Wagshul

Eide

Madsen

2011

Fluids Barriers CNS

386

311

View full text Add to dashboard Cite

show abstract

“…This technique is widely used for the clinical diagnosis of hydrocephalus. Kim et al (19) recommended phase-contrast MRI as a significant method for the evaluation of the position and severity of obstruction in patients with obstructive hydrocephalus. In the current study, the results of post-aqueductoplasty phase-contrast MRI indicated that the aqueduct was unobstructed in 23 patients.…”

Section: Discussionmentioning

confidence: 99%

Application of phase-contrast cine magnetic resonance imaging in endoscopic aqueductoplasty

Chen

Zheng

Xiao

et al. 2013

Experimental and Therapeutic Medicine

View full text Add to dashboard Cite

The aim of this study was to evaluate the application of phase-contrast cine magnetic resonance imaging (MRI) in endoscopic aqueductoplasty (EA) for patients with obstructive hydrocephalus. The clinical diagnosis of hydrocephalus caused by aqueduct obstruction in 23 patients was confirmed by phase-contrast cine MRI examination. The patients were treated with EA and MRI was repeated during the follow-up. The cerebrospinal fluid (CSF) flow velocity in the aqueduct was measured to determine whether the aqueduct was obstructed. The results of phase-contrast cine MRI examinations indicated that there was no CSF flow in the aqueduct for all patients prior to surgery. Aqueductoplasty was successfully performed in all patients. The results of phase-contrast cine MRI examinations performed a week after surgery demonstrated an average CSF flow velocity of 4.74±1.77 cm/sec. During the follow-up, intracranial hypertension recurred in two patients in whom CSF flow was not observed in the aqueduct by the phase-contrast cine MRI scan. Aqueduct re-occlusion was revealed by an endoscopic exploration. By measuring the CSF flow velocity, phase-contrast cine MRI accurately identifies aqueduct obstruction. Cine MRI is a nontraumatic, simple and reliable method for determining whether the aqueduct is successfully opened following aqueductoplasty.

show abstract

“…49 The wide physiological range of the temporal, velocity, and flow parameters is striking. 6,7,28,34,59 This normal variation is mainly related to the size and anatomy of CSF spaces, size of blood vessels, systolic and diastolic arterial blood pressure, heart rate, jugular venous flow, compliance of surrounding brain tissue, 1,6,12,49 and respiration. 41,52 Neurosurg.…”

Section: Discussionmentioning

confidence: 99%

“…3,17,28,60 The results of these measurements have yielded considerable information on the physiology of the normal CSF circulation. 1,6,7,9,17,23,42,43 In addition, pathological CSF flow dynamics in communicating and obstructive hydrocephalus, 11,22,[32][33][34]44,54 Chiari malformation, 8 cystic lesion, 15 and cervical spondylosis 60 have been analyzed. With the increasing frequency of neuroendoscopic procedures, cine MR imaging has been recommended for evaluating the patency of third ventriculostomies.…”

mentioning

confidence: 99%

Analysis of aqueductal cerebrospinal fluid flow after endoscopic aqueductoplasty by using cine phase-contrast magnetic resonance imaging

Schroeder¹,

Schweim²,

Schweim³

et al. 2000

FOC

View full text Add to dashboard Cite

Object The purpose of this prospective study was to evaluate aqueductal cerebrospinal fluid (CSF) flow after endoscopic aqueductoplasty. In all patients, preoperative magnetic resonance (MR) imaging revealed hydrocephalus caused by aqueductal stenosis and lack of aqueductal CSF flow. Methods In 14 healthy volunteers and in eight patients with aqueductal stenosis who had undergone endoscopic aqueductoplasty, aqueductal CSF flow was investigated using cine cardiac-gated phase-contrast MR imaging. For qualitative evaluation of CSF flow, the authors used an in-plane phase-contrast sequence in the midsagittal plane. The MR images were displayed in a closed-loop cine format. Quantitative through-plane measurements were performed in the axial plane perpendicular to the aqueduct. Evaluation revealed no significant difference in aqueductal CSF flow between healthy volunteers and patients with regard to temporal parameters, CSF peak and mean velocities, mean flow, and stroke volume. All restored aqueducts have remained patent 7 to 31 months after surgery. Conclusions Aqueductal CSF flow after endoscopic aqueductoplasty is similar to aqueductal CSF flow in healthy volunteers. The data indicate that endoscopic aqueductoplasty seems to restore physiological aqueductal CSF flow.

show abstract

Cine MR CSF Flow Study in Hydrocephalus: What are the Valuable Parameters?

Cited by 13 publications

References 9 publications

The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility

The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility

Application of phase-contrast cine magnetic resonance imaging in endoscopic aqueductoplasty

Analysis of aqueductal cerebrospinal fluid flow after endoscopic aqueductoplasty by using cine phase-contrast magnetic resonance imaging

Contact Info

Product

Resources

About