Ciliary Beating Frequency in Chronic Sinusitis

Effects of rapid maxillary expansion on nasal mucociliary clearance

“…On the other hand, RME has been suggested as a treatment option for rhinostenosis caused by a septal deformity, nasal infection, allergic rhinitis, and obstructive sleep apnea, 19,20 which were reported as having prolonged STTs. [21][22][23][24] In our study, STT was decreased after both expansion and retention in the RME group, compared with the control group ( Table 2). It is possible that this is primarily the result of improved mucociliary function, which in turn is due to the increase in nasal cavity volume, decrease in nasal resistance, and improvement in air flow after RME.…”

Mucociliary clearance – a critical upper airway host defense mechanism and methods of assessment

“…Although multiple etiologies contribute to the development of CRS, a common pathophysiologic sequelae is ineffective sinonasal mucociliary clearance, resulting in stasis of sinonasal secretions with subsequent infection and/or persistent inflammation. Although the literature is contradictory regarding mucus viscosity [68][69][70], and basal ciliary beat frequency [69,[71][72][73][74], in CRS, recent work has suggested that a subset of patients with CRS have a blunted ciliary response to environmental stimuli [35 ].…”

Electron Microscopy Assessment of the Recovery of Sinus Mucosa after Sinus Surgery

“…It is known that infections disturb mucosal defence by causing impaired mucociliary function. This may be due to bacterial endotoxins, loss of ciliated cells and cilia, reduced ciliary beating activity or changes in the composition of respiratory mucus (1,2). Morphological changes in the respiratory mucosa and cilia have been reported in both acute and chronic infections and ultrastructural changes seen in the cilia of patients with chronic sinusitis have been considered to be the cause of impairment of ciliary beating (3 Á/5).…”