Cilia and Nodal Flow in Asymmetry: An Engineering Perspective
Madisyn Messmore,
Alain J. Kassab,
Ray O. Prather
et al.
Abstract:Over the past several years, cilia in the primitive node have become recognized more and more for their contribution to development, and more specifically, for their role in axis determination. Although many of the mechanisms behind their influence remain undocumented, it is known that their presence and motion in the primitive node of developing embryos is the determinant of the left-right axis. Studies on cilial mechanics and nodal fluid dynamics have provided clues as to how this asymmetry mechanism works, … Show more
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