Ciguatera

Heimann, Kirsten; Sparrow, Leanne

doi:10.1016/b978-0-12-800776-1.00037-6

Cited by 5 publications

(11 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ciguatera is a complex syndrome caused by large molecular weight polyether toxins synthesised by marine algae of the genus Gambierdiscus 1 2. The algae are consumed by herbivorous fish, which are in turn consumed by carnivorous fish.…”

Section: Discussionmentioning

confidence: 99%

“…Human consumption of these fish results in ciguatera intoxication. At least 12 different ciguatoxins have been characterised,1 with Pacific ciguatoxins showing significantly greater potency than Caribbean ciguatoxins 3…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…An estimated 50 000–5 00 000 cases of ciguatera occur annually in tropical and subtropical regions associated with coral reefs 1. The uncertainty regarding the true incidence is due to the remoteness of many ciguatera endemic areas, and to the fact that many cases are mild and never present to healthcare facilities 1. However, an increase in global sea temperatures is predicted to lead to the spread of ciguatera beyond traditional endemic areas,2 and the globalisation of trade in coral reef fish for human consumption has resulted in sporadic cases occurring in developed countries far away from endemic areas 1 2.…”

Section: Introductionmentioning

confidence: 99%

“…The uncertainty regarding the true incidence is due to the remoteness of many ciguatera endemic areas, and to the fact that many cases are mild and never present to healthcare facilities 1. However, an increase in global sea temperatures is predicted to lead to the spread of ciguatera beyond traditional endemic areas,2 and the globalisation of trade in coral reef fish for human consumption has resulted in sporadic cases occurring in developed countries far away from endemic areas 1 2. We describe the case of a 58-year-old man who presented to the emergency department of a Caribbean hospital with gastrointestinal symptoms following a meal of barracuda and was found to have a junctional bradycardia.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Junctional bradycardia caused by ciguatera intoxication

Raman¹,

Coppes

Hellingman

et al. 2019

BMJ Case Rep

View full text Add to dashboard Cite

Ciguatera is a common but underreported tropical disease caused by the consumption of coral reef fish contaminated by ciguatoxins. Gastrointestinal and neurological symptoms predominate, but may be accompanied by cardiovascular features such as hypotension and sinus bradycardia. Here, we report an unusual case of junctional bradycardia caused by ciguatera in the Caribbean; to our knowledge, the first such report from the region. An increase in global sea temperatures is predicted to lead to the spread of ciguatera beyond traditional endemic areas, and the globalisation of trade in coral reef fish has resulted in sporadic cases occurring in developed countries far away from endemic areas. This case serves as a reminder to consider environmental intoxications such as ciguatera within the differential diagnosis of bradycardias.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Junctional bradycardia caused by ciguatera intoxication

Raman¹,

Coppes

Hellingman

et al. 2019

BMJ Case Rep

View full text Add to dashboard Cite

show abstract

Development and validation of PCR-RFLP assay for identification of Gambierdiscus species in the Greater Caribbean Region

Lozano-Duque¹,

Richlen

Smith

et al. 2018

J Appl Phycol

View full text Add to dashboard Cite

The genus Gambierdiscus is a recognized group of marine epiphytic-benthic dinoflagellates that produce the toxins that cause ciguatera fish poisoning (CFP). To date, thirteen species and six ribotypes of Gambierdiscus have been identified, and multiple species commonly co-occur within a single site or epiphyte community. Toxicity can vary by species, thus it is important to be able to differentiate among species for research and monitoring purposes. Gambierdiscus species have very similar morphological characteristics and are difficult or impossible to distinguish using light microscopy. DNA sequencing has been an important tool in the definition of Gambierdiscus species, but it can be time-consuming and relatively expensive. To provide an alternative approach, a PCR-RFLP protocol was developed for efficient, rapid, and cost-effective identification of Gambierdiscus strains isolated from the Gulf of Mexico and Caribbean Sea, where CFP cases and Gambierdiscus spp. have been reported. The assay targets the D1-D2 hypervariable regions of the large subunit ribosomal RNA gene and uses a single restriction enzyme, BsrI. This method produces distinct RFLP banding patterns for the six species of Gambierdiscus reported from the Gulf of Mexico and Caribbean Sea, and also distinguishes them from four Pacific endemic species. This method was successfully used to type 465 clonal isolates of Gambierdiscus from the U.S. Virgin Islands and Akumal Beach - Mexico This BsrI PCR-RFLP method expands the tools available to researchers and managers engaged in monitoring activities and ecological studies.

show abstract

The Prevalence of Marine Lipophilic Phycotoxins Causes Potential Risks in a Tropical Small Island Developing State

Zhu,

Li,

et al. 2024

Environ. Sci. Technol.

View full text Add to dashboard Cite

Tropical small island developing states (SIDS), with their geographical isolation and limited resources, heavily rely on the fisheries industry for food and revenue. The presence of marine lipophilic phycotoxins (MLPs) poses risks to their economy and human health. To understand the contamination status and potential risks, the Republic of Kiribati was selected as the representative tropical SIDS and 55 species of 256 coral reef fish encompassing multiple trophic levels and feeding strategies were collected to analyze 17 typical MLPs. Our results showed that the potential risks of ciguatoxins were the highest and approximately 62% of fish species may pose risks for consumers. Biomagnification of ciguatoxins was observed in the food web with a trophic magnification factor of 2.90. Brevetoxin-3, okadaic acid, and dinophysistoxin-1 and -2 were first reported, but the risks posed by okadaic acid and dinophysistoxins were found to be negligible. The correlation analysis revealed that fish body size and trophic position are unreliable metrics to indicate the associated risks and prevent the consumption of contaminated fish. The potential risks of MLPs in Kiribati are of concern, and our findings can serve as valuable inputs for developing food safety policies and fisheries management strategies specific to tropical SIDS contexts.

show abstract

Ciguatera

Cited by 5 publications

References 31 publications

Junctional bradycardia caused by ciguatera intoxication

Junctional bradycardia caused by ciguatera intoxication

Development and validation of PCR-RFLP assay for identification of Gambierdiscus species in the Greater Caribbean Region

The Prevalence of Marine Lipophilic Phycotoxins Causes Potential Risks in a Tropical Small Island Developing State

Contact Info

Product

Resources

About