Cigarette Smoking and Thrombotic Coagulation of Human Blood

Engelberg, Hyman; Futterman, M.

doi:10.1080/00039896.1967.10664729

Cited by 7 publications

(1 citation statement)

References 12 publications

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“…Smoking causes a decrease in the flow of blood to the extremities and a reduction in the skin temperature of the digits (36). Several studies have demonstrated increased platelet adhesiveness and acceleration of thrombus formation in the blood of cigarette smokers (37, 38). There also is good evidence that smoking adversely affects the long‐term results of vascular reconstructive surgery (39, 40).…”

Section: Measures For Conservative Managementmentioning

confidence: 99%

Surgical Aspects of Peripheral Vascular Disease*

Imbembo

Smith

1974

J American Geriatrics Society

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This article reviews current surgical concepts regarding the management of elderly patients with peripheral vascular disease. The indications for surgical reconstruction may be either relative or absolute, but only absolute indications (e.g., incipient gangrene) apply in the elderly. A review of the natural history of the disease shows that although some cases remain stable for long periods, many progress to a state of serious deterioration with painful intermittent claudication, incipient gangrene and threatened loss of the limb. The mechanisms of deterioration include thrombosis, embolism and minor trauma. Peripheral vascular occlusive disease is only one manifestation of a generalized disease process, and vascular reconstruction is only a palliative measure. However, since high morbidity and mortality are associated with amputation, reconstruction should always be considered, even in the geriatric patient. The aorto‐iliac reconstruction technique is associated with a fairly low mortality rate and a limb‐salvage rate of 85 per cent; simpler alternatives are available in high‐risk patients. For femoro‐popliteal procedures the mortality rate is low and the limb‐salvage rate is 75 per cent. Such results emphasize that vascular reconstruction usually is preferable to amputation. Measures for conservative management, particularly in aged patients, are discussed.

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Section: Measures For Conservative Managementmentioning

confidence: 99%

Surgical Aspects of Peripheral Vascular Disease*

Imbembo

Smith

1974

J American Geriatrics Society

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Blood coagulation studies in a long-term experiment on dietary prevention of ischemic heart disease

et al. 1974

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Thumb Replantation: Survival Factors and Re-Exploration in 122 Cases

Arakaki

Tsai

1993

Journal of Hand Surgery

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We analyzed 122 cases of replantation following complete amputation of the thumb and correlated various factors with rates of survival. The overall survival rate of thumb replantation was 71%. The type of amputation markedly affected survival rate. In minimally damaged amputations, the time period from injury to the start of surgery was the only significant factor related to survival. Other factors such as age, smoking history, amputation level, the number of vessels reconstructed and the method used did not relate statistically to survival. With avulsion amputations, the survival rate of replantation at and proximal to the MP joint was significantly better than replantation distal to the MP joint. 20 thumbs required re-exploration for vascular compromise; nine of these were salvaged (45%).

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Cigarette Smoking and Thrombotic Coagulation of Human Blood

Cited by 7 publications

References 12 publications

Surgical Aspects of Peripheral Vascular Disease*

Surgical Aspects of Peripheral Vascular Disease*

Blood coagulation studies in a long-term experiment on dietary prevention of ischemic heart disease

Thumb Replantation: Survival Factors and Re-Exploration in 122 Cases

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