Cigarette smoking and self-assessed upper airway health

Kjærgaard, Thomas; Cvancarova, Milada; Steinsvåg, Sverre K.

doi:10.1007/s00405-010-1287-y

Cited by 9 publications

(7 citation statements)

References 55 publications

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“…21 It is unclear if these effects are temporary or permanent. 4,22 A literature review by Reh et al concluded that cigarette smoke – both active and secondhand—does contribute to CRS pathogenesis. 3…”

Section: Discussionmentioning

confidence: 99%

General Complications after Endoscopic Sinus Surgery in Smokers: A 2005-2016 NSQIP Analysis

Teitelbaum

Grasse

Quan

et al. 2020

Ann Otol Rhinol Laryngol

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Background: Exposure to cigarette smoke has been associated with a higher incidence of postoperative complications across a variety of surgical specialties. However, it is unclear if smoking increases this risk after endoscopic sinus surgery (ESS). Because complication rates after ESS are relatively low, a large national database allows for a statistically meaningful study of this topic. Methods: The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) dataset from 2005 to 2016 was analyzed. Patients who underwent ESS were identified. Thirty-day postoperative complication rates between smokers and nonsmokers were compared. Complications included infection, thromboembolic events, reintubation, readmission, acute renal failure, and cardiovascular events. Results: 921 patients who underwent ESS were identified. 182 (20%) were smokers and 739 (80%) were nonsmokers. 609 patients underwent outpatient ESS, while 312 patients underwent inpatient ESS. A total of 12 patients experienced postoperative surgical site infections involving the deeper tissues beyond the wound (organ/space SSI). On univariate analysis, smoking was associated with a higher incidence of organ/space SSI ( P = .0067) and pulmonary embolism ( P = .0321) after ESS. On multivariate logistic regression, smoking was associated with increased odds (4.495, 1.11- 8.17, P = .0347) of organ/space SSI after ESS. Conclusions: This study demonstrates an association between exposure to cigarette smoke and potentially serious surgical site infections in the 30-day postoperative period after ESS. Our findings may help when counseling smokers who are considering ESS. Further study is required to understand the nature of these infections and ways to prevent them. Level of Evidence: 2c (“health outcomes”)

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Section: Discussionmentioning

confidence: 99%

General Complications after Endoscopic Sinus Surgery in Smokers: A 2005-2016 NSQIP Analysis

Teitelbaum

Grasse

Quan

et al. 2020

Ann Otol Rhinol Laryngol

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“…Additionally, questionnaires that assess the influence of air pollution exposure on the airways have been used previously [21-24], using specific symptoms attributable to acute air pollution exposure as recommended by the American Thoracic Society [25]. For example, airway narrowing due to inflammation and excessive mucous secretion (as an immune response to airway irritation by pollutants) can induce coughing and chest tightness or wheezing, as well as reduce lung function indicated by lowered peak expiratory flow rates [26].…”

Section: Introductionmentioning

confidence: 99%

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

et al. 2013

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BackgroundBicycle commuting in an urban environment of high air pollution is known to be a potential health risk, especially for susceptible individuals. While risk management strategies aimed to reduce exposure to motorised traffic emissions have been suggested, only limited studies have assessed the utility of such strategies in real-world circumstances.ObjectivesThe potential to lower exposure to ultrafine particles (UFP; < 0.1 μm) during bicycle commuting by reducing proximity to motorised traffic was investigated with real-time air pollution and intermittent acute inflammatory measurements in healthy individuals using their typical higher proximity, and an alternative lower proximity, bicycle commute route.MethodsThirty-five healthy adults (mean ± SD: age = 39 ± 11 yr; 29% female) completed two return trips, one each in the condition of their typical route (HIGH) and a pre-determined alternative route of lower proximity to motorised traffic (LOW); proximity being determined by the proportion of on-road cycle paths. Particle number concentration (PNC) and diameter (PD) were monitored in-commute in real-time. Acute inflammatory indices of respiratory symptoms (as a scalar of frequency from very low to very high / 1 to 5), lung function and spontaneous sputum (for inflammatory cell analyses) were collected immediately pre-commute, and immediately and three hours post-commute.ResultsIn the condition of LOW, compared to in the condition of HIGH, there was a significant decrease in mean PNC (1.91 x e4 ± 0.93 × e4 ppcc vs. 2.95 × e4 ± 1.50 × e4 ppcc; p ≤ 0.001), and the mean frequency of in-commute offensive odour detection (2.1 vs. 2.8; p = 0.019), dust and soot observation (1.7 vs. 2.3; p = 0.038) and nasopharyngeal irritation (1.5 vs. 1.9; p = 0.007). There were no significant differences between LOW and HIGH in the commute distance and duration (12.8 ± 7.1 vs. 12.0 ± 6.9 km and 44 ± 17 vs. 42 ± 17 min, respectively), or other indices of acute airway inflammation.ConclusionsExposure to PNC and offensive odour, and nasopharyngeal irritation, can be significantly lowered when utilising a route of lower proximity to motorised traffic whilst bicycle commuting, without significantly affecting commute distance or duration. This may bring health benefits for both healthy and susceptible individuals.

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“…In the present study questions about the following 9 symptoms PNIF value of 120 -140 L/min. among healthy subjects (20,21) .…”

Section: Nose Symptom Visual Analogue Scale (Nose-vas)mentioning

confidence: 97%

“…VAS is a psychometric response scale to measure the intensity of various symptoms. Nose-VAS is a questionnaire developed to be used to quantify the patient reported level of nasal obstruction, as well as other sino-nasal related symptoms on a 100 mmm linear scale ranging from no obstruction/no symptom to complete obstruction/ most intense symptom possible (20) . In the present study questions about the following 9 symptoms PNIF value of 120 -140 L/min.…”

Section: Nose Symptom Visual Analogue Scale (Nose-vas)mentioning

confidence: 99%

Correlation between Excessive Daytime Sleepiness (EDS) and self-reported and objective nasal characteristics

Hoven¹,

Aarstad²,

Bjorvatn³

et al. 2018

Rhin

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Background: The aim of the present study was to explore the relationship between excessive daytime sleepiness (EDS), Peak Nasal Inspiratory Flow (PNIF), and patient reported symptoms from the nose. Methology: Six hundred and fifty one consecutive patients referred to a hospital on suspicion of sleep related breathing disorder (SRBD) were included in the study. Daytime sleepiness was assessed by Epworth Sleepiness Scale (EpSS). Nasal airflow was measured with Peak Nasal Inspiratory Flow (PNIF). Symptoms of sino-nasal dysfunction and diseases were graded on Visual Analogue Scales (VAS). Results: EpSS score was not correlated with nasal flow as measured by PNIF or nasal obstruction-VAS scores. There were significant associations between daytime sleepiness and patient-reported VAS-scores on nasal discharge, headache, coughing, general health and to some extent sneezing when age, gender, BMI and reported co-morbidity levels were adjusted for. Conclusion: A clinical implication of this is that patients with EDS may be evaluated and treated for sino-nasal disease, while medical and surgical measures to open the nose per se may not be effective therapeutic options. A scientific implication is that the relationship between SRBD and sino-nasal disease should be further investigated.

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Cigarette smoking and self-assessed upper airway health

Cited by 9 publications

References 55 publications

General Complications after Endoscopic Sinus Surgery in Smokers: A 2005-2016 NSQIP Analysis

General Complications after Endoscopic Sinus Surgery in Smokers: A 2005-2016 NSQIP Analysis

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

Correlation between Excessive Daytime Sleepiness (EDS) and self-reported and objective nasal characteristics

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