Cigarette Smoking and Changes in Respiratory Findings

Comstock, George W.; Brownlow, Wilfred J.; Stone, Richard E.; Sartwell, Philip E.

doi:10.1093/aje/kwn321

Cited by 3 publications

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“…A decrease in pulmonary function is smokers have been well established. Studies have reported forced expiratory volume in 1 sec (FEV1) to be lowest in cigarette smokers [7]. A lower and a rapid decline in lung function in smokers when compared to age and height matched non-smokers has also been reported [8].…”

Section: Introductionmentioning

confidence: 99%

Pulmonary function, white blood corpuscles & haemoglobin levels in asymptomatic light smokers and non-smokers

Rao

Pavithan²,

Das

2017

Int J Med Res Rev

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Context: Smoking, a risk factor for several diseases has also been reported as the largest preventable cause of morbidity and mortality globally. Tobacco smoking is associated with a decrease in lung function in smokers when compared to non-smokers. Aims: To study and compare pulmonary function, WBC count and Hb levels in asymptomatic light smokers and non-smokers. Settings and Design: Case control study. Methods and Material: Patient relatives or subjects who had come for health check with a known history of smoking and apparently asymptomatic were recruited as our study subjects (n = 49). Healthy volunteers were also recruited from patient relatives. Subjects without any known history of smoking were selected as controls (n = 50). Statistical analysis used: Data was analysed using SPSS V-19. P value ≤0.05 was considered significant. Results: A statistically significant difference was found in total leucocyte count in smokers (P = 0.004) when compared to non-smokers. There was also a statistically significant increase in absolute neutrophil (P = 0.021), monocyte (P = 0.004) and eosinophil (P = 0.075) counts in smokers. FEV1/FVC (P = 0.005) and FEF 75 (P = 0.027) was significantly higher in non-smokers when compared to smokers. No significant difference was observed in haemoglobin concentration and differential leucocyte count, pulse rate, systolic pressure, diastolic pressure and rate pressure product among the two groups. Conclusions: The present study gives ample evidence for the damage to the respiratory system along with activation of immune system as evident from a significant lowering of small airway patency and increased white cell counts.

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Section: Introductionmentioning

confidence: 99%

Pulmonary function, white blood corpuscles & haemoglobin levels in asymptomatic light smokers and non-smokers

Rao

Pavithan²,

Das

2017

Int J Med Res Rev

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Ebeiedinone and peimisine inhibit cigarette smoke extract-induced oxidative stress injury and apoptosis in BEAS-2B cells

Liu,

Zhu,

Aga

et al. 2024

Cell Stress and Chaperones

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Lung Function and Respiratory Symptoms in Male Palestinian Farmers

Sham'a

Skogstad

Nijem

et al. 2010

Archives of Environmental & Occupational Health

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In a cross-sectional study of 250 farmers aged 22 to 77 years, of whom 36.4% are smokers, the authors aimed at describing lung function and respiratory symptoms and to estimate associations with exposures to pesticides and dust. Lung function was measured using a spirometer. Respiratory symptoms and exposure levels were self-reported based on a modified standardized questionnaire. Mean forced vital capacity (FVC) was 4.20 L (SD = 0.93 L), 95.51% of predicted as compared to European standards. Mean forced expiratory volume in one second (FEV(1)) was 3.28 L (SD = 0.80 L), 91.05% of predicted. The authors found high symptom prevalences: 14.0% for chronic cough; 26.4% for wheeze; and 55.2% for breathlessness. There was no clear association between exposure to pesticides or dust and lung function or between such exposures and respiratory symptoms. However, a significant association was found between smoking and respiratory symptoms such as chronic cough, cough with phlegm, and wheezes. The lack of farm exposure associations could be due to improvement in farmers' awareness to pesticides hazards as well as regulations of pesticide import, or because of inherent problems with the experimental design. Farmers who kept animals and poultry seem to have less respiratory symptoms and better lung function.

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Cigarette Smoking and Changes in Respiratory Findings

Cited by 3 publications

References 0 publications

Pulmonary function, white blood corpuscles & haemoglobin levels in asymptomatic light smokers and non-smokers

Pulmonary function, white blood corpuscles & haemoglobin levels in asymptomatic light smokers and non-smokers

Ebeiedinone and peimisine inhibit cigarette smoke extract-induced oxidative stress injury and apoptosis in BEAS-2B cells

Lung Function and Respiratory Symptoms in Male Palestinian Farmers

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