Cigarette Smoking, Alcohol and Caffeine Consumption, and Bone Mineral Density in Postmenopausal Women

Grainge, Matthew J.; Coupland, Carol; Cliffe, S. J.; Chilvers, C. E. D.; Hosking, D. J.

doi:10.1007/s001980050075

Cited by 92 publications

(55 citation statements)

References 19 publications

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“…While excessive alcohol intake negatively affects BMD (28), moderate alcohol consumption seems to have a positive effect (21,29,30). Other studies, however, have failed to find such an effect for smoking and alcohol (18,21,(31)(32)(33).…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Osteoporosis in the Thrace Region of Turkey: A Community-Based Study

Keskin¹,

Cekin²,

Gündüz³

et al. 2014

Turk J Phys Med Rehab

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Objective: This study was planned as a community-based research study to estimate the prevalence of osteoporosis and explore related risk factors in the Thrace region of Turkey. Material and Methods:The community-based study involved a total of 620 people, 498 women and 122 men, aged between 40 and 89 years. A questionnaire on the medical history and lifestyles of the participants was applied with a face-to-face interview. Body weight height, and arm span of each participant were measured, together with bone mineral density at the middle phalanges of the second, third, and fourth digits of the non-dominant hand using dual-energy X-ray laser absorptiometry. Results: Age, clothing, lack of regular exercise, and giving birth to more than two children seem to contribute to osteoporosis, while high education, high economic level, tea and moderate alcohol consumption, oral contraceptive use, and hormone replacement therapy seem to retard osteoporosis. Osteoporotic patients had more fractures in the past. Height and weight were significantly lower in osteoporotic women. Conclusion: Lifestyle affects the prevalence of osteoporosis. Drinking tea and alcohol seems to be controversial with regard to osteoporosis risk. Key Words: Osteoporosis, bone density, risk factors, lifestyle Özet Amaç: Çalışma, Türkiye'nin Trakya bölgesinde osteoporoz prevalansını kestirmek ve ilgili risk faktörlerini ortaya çıkarmak amacıyla tasarlandı. Gereç ve Yöntemler: Toplum temelli çalışma, yaşları 40 ile 89 arasında, 498 kadın ve 122 erkekten oluşan toplam 620 kişiyi kapsadı. Çalışmaya katılanların tıbbi geçmişlerini ve yaşam tarzlarını sorgulayan bir anket yüz yüze gerçekleştirildi. Kilo, boy, kulaç uzunluğu ve Dual-Enerji X-ray lazer absorpsiyometri ile baskın olmayan elin 2, 3 ve 4.parmaklarının orta falankslarından kemik mineral yoğunluğu ölçüldü. Bulgular: Yaş, giyinme, düzenli egzersiz yokluğu ve doğum sayısı osteoporoz ihtimalini arttırıyor görünürken iyi eğitimli olma, ekonomik seviyenin yüksekliği, çay ve hafif alkol tüketimi, doğum kontrol hapı kullanımı ve hormon replasman tedavisi osteoporozu yavaşlatıyor görünmektedir. Osteoporotik hastaların geçmişlerinde daha fazla kırık tespit edilmiştir. Osteoporotik kadınların boyu ve kilosu belirgin biçimde daha az bulunmuştur. Sonuç: Yaşam stili osteoporoz prevalansını etkilemektedir. Çay ve alkol içmenin osteoporoz riski açısından etkisi tartışmalı görünmektedir.

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Section: Discussionmentioning

confidence: 99%

The Prevalence of Osteoporosis in the Thrace Region of Turkey: A Community-Based Study

Keskin¹,

Cekin²,

Gündüz³

et al. 2014

Turk J Phys Med Rehab

View full text Add to dashboard Cite

show abstract

“…However, others showed no significant association between alcohol intake and BMD (24)(25)(26)(27)(28) , and one reported a negative relationship between BMD at the lumbar spine and lifetime beer consumption (29) .…”

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confidence: 99%

Alcohol consumption and bone mineral density in elderly women

Sommer

Erkkilä

Järvinen

et al. 2012

Public Health Nutr.

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Objective: Findings regarding alcohol consumption and bone mineral density (BMD) in elderly women have been inconsistent. The objective of the present study was to explore the association of alcohol intake with BMD in elderly women. Design: This cohort study included women from the population-based Kuopio Osteoporosis Risk Factor and Prevention -Fracture Prevention Study (OSTPRE-FPS). Alcohol intake and potential confounders were assessed at baseline and after 3 years of follow-up using a lifestyle questionnaire. In addition, an FFQ was distributed in the third year to measure dietary intake, including alcohol. Women underwent BMD measurements at the femoral neck and lumbar spine at baseline and after 3 years of follow-up. Setting: Kuopio Province, Finland. Subjects: Three hundred elderly women (mean age 67?8 years) who provided both BMD measurements and FFQ data. Results: Alcohol consumption estimated from the FFQ and lifestyle questionnaire was significantly associated with BMD at both measurement sites after adjustment for potential confounders, including lifestyle and dietary factors (P , 0?05). Using the FFQ, women drinking .3 alcoholic drinks/week had significantly higher BMD than abstainers, 12?0 % at the femoral neck and 9?2 % at the lumbar spine. Results based on the lifestyle questionnaire showed higher BMD values for all alcohol-consuming women at the femoral neck and for women drinking 1-3 alcoholic beverages/week at the lumbar spine, compared with non-users. Conclusions:The results from OSTPRE-FPS suggest that low to moderate alcohol intake may exert protective effects on bone health in elderly women.

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“…[10][11][12][13] Furthermore, multiple myeloma is associated with systemic osteoporosis as a result of increased osteoclastic activity. 14 ABMT patients also may have general risk factors for osteoporosis that include older age, 15 thin body habitus, 16,17 a family history of osteoporosis, 18 smoking, 19,20 and physical inactivity. 16 While survivors of ABMT have significant risks for decreased BMD, little is known about the incidence or predictive variables for osteopenia and osteoporosis in this population.…”

mentioning

confidence: 99%

Decreased bone mineral density is common after autologous blood or marrow transplantation

Schimmer

Mah

Bordeleau

et al. 2001

Bone Marrow Transplant

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Summary:Survivors of autologous blood or marrow transplantation (ABMT) are predisposed to decreased bone mineral density (BMD), but data are lacking on the incidence and risk factors for this condition. Therefore, we measured BMD in 64 of 68 consecutive ABMT survivors (35 men and 29 women) attending the University of Toronto ABMT long-term follow-up clinic. Patients were evaluated a median of 4.2 years (range: 4.9 months-11.4 years) after ABMT. Median age at evaluation was 49.6 years (range: 23.5-68.2 years). At the L1-L4 vertebrae, 17 (26%) patients (eight men and nine women) had osteopenia and one male (2%) had osteoporosis. Mean BMD at L1-L4 did not differ from healthy young adults or age and sex matched controls. At the femoral neck, 30 patients (46%) (18 men and 12 women) had osteopenia and five (8%) (two men and three women) had osteoporosis. Mean BMD at the femoral neck was significantly lower than in healthy young adults and age-and sex-matched controls. By regression analysis, patients with decreased BMD were older than those with normal BMD (P = 0.02). Gender, body mass index, time from BMT to evaluation and presence of hypogonadism were not associated with decreased BMD. Treatment of decreased bone density was instituted and follow-up data were obtained 1 year after treatment in 22 of 39 patients with reduced BMD. Nineteen (86%) patients had stabilization or improvement of their bone density at follow-up. We conclude that, after ABMT, over half of the patients have evidence of osteopenia or osteoporosis. Men and women were equally affected. In our study, only older age at evaluation was predictive for loss of BMD. We recommend the measurement of BMD as an integral component to the follow-up of ABMT patients. Bone Marrow Transplantation (2001) As the number of long-term survivors of autologous blood or marrow transplantation (ABMT) increases, greater attention is turning to the late complications of this procedure. One such complication is decreased bone mineral densityosteopenia and osteoporosis. Osteopenia is a systemic condition characterized by reduced bone mass and increased susceptibility to bone fracture. Osteoporosis is a more severe reduction in bone mass and a greater susceptibility to bone fracture.In the short term, osteoporosis seems trivial compared with a diagnosis of cancer, but for those cured of their disease, decreased bone mineral density contributes to chronic morbidity and mortality in the form of bone fractures. For example, 50% of patients who sustain an osteoporosisrelated hip fracture require assistance with activities of daily living 1 and elderly patients who suffer an osteoporosis-related hip fracture have an increased 1-year mortality of 12-37%. 2 ABMT predisposes to decreased BMD through early and late acting mechanisms. ABMT is associated with an acute increase in bone turnover due to the high-dose chemotherapy, marrow reinfusion and G-CSF administration, but effects on long-term bone density are unknown. [3][4][5] The late effects of ABMT on BMD are primarily due to t...

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Cigarette Smoking, Alcohol and Caffeine Consumption, and Bone Mineral Density in Postmenopausal Women

Cited by 92 publications

References 19 publications

The Prevalence of Osteoporosis in the Thrace Region of Turkey: A Community-Based Study

The Prevalence of Osteoporosis in the Thrace Region of Turkey: A Community-Based Study

Alcohol consumption and bone mineral density in elderly women

Decreased bone mineral density is common after autologous blood or marrow transplantation

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