Cigarette, alcohol, and caffeine consumption: risk factors for spontaneous abortion

Rasch, Vibeke

doi:10.1034/j.1600-0412.2003.00078.x

Cited by 239 publications

(105 citation statements)

References 26 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cigarette smoking, alcohol and moderate-to-heavy caffeine and cocaine use58 59 may be associated with sporadic miscarriages; however, the relationship between these factors and recurrent miscarriage is unclear.…”

Section: Aetiology Of and Risk Factors For Recurrent Miscarriagementioning

confidence: 99%

Recurrent miscarriage: causes, evaluation and management

Garrido¹,

Alijotas‐Reig

2015

Postgraduate Medical Journal

209

135

View full text Add to dashboard Cite

Recurrent miscarriage is frustrating for the physician and a heartbreaking experience for the patient. Approximately 5% of couples trying to conceive have two consecutive miscarriages. Despite a thorough study of patients, the aetiology of this common obstetric complication is unknown in 50% of cases. Known causes include abnormal chromosomes, endocrinological disorders and uterine abnormalities. Although antiphospholipid antibodies have been demonstrated in miscarriages, the role played by alloimmune mechanisms remains unclear. New immunological approaches such as natural killer cells, regulatory T cells, tumour necrosis factor α, cell-derived microparticles, leptin, certain glycoproteins and cytokines should be considered. The management of thyroid diseases and immunological disorders is continuously evolving. Several genetic diagnostic procedures such as parental karyotyping and preimplantation genetic screening should probably not be used routinely. Antiphopholipid syndrome and some recurrent miscarriage-related endocrinological disorders can be effectively treated. Finally, new therapeutic approaches and the pleiotropic effects of old ones have led to improved fetal-maternal outcomes.

show abstract

Section: Aetiology Of and Risk Factors For Recurrent Miscarriagementioning

confidence: 99%

Recurrent miscarriage: causes, evaluation and management

Garrido¹,

Alijotas‐Reig

2015

Postgraduate Medical Journal

209

135

View full text Add to dashboard Cite

show abstract

“…However, the literature has yielded inconsistent results regarding the existence of an association. Several studies have found an association between alcohol consumption during pregnancy and miscarriage(Andersen, Andersen, Olsen, Gronbaek, & Strandberg-Larsen, 2012; Armstrong, McDonald, & Sloan, 1992; Chiodo et al, 2012; Harlap & Shiono, 1980; Henriksen et al, 2004; Kesmodel, Wisborg, Olsen, Henriksen, & Secher, 2002; Kline, Shrout, Stein, Susser, & Warburton, 1980; Maconochie, Doyle, Prior, & Simmons, 2007; Rasch, 2003; Windham, Von Behren, Fenster, Schaefer, & Swan, 1997). However, others, including two systematic reviews published in 2006 and 2007, have not(Cavallo, Russo, Zotti, Camerlengo, & Ruggenini, 1995; Henderson, Gray, & Brocklehurst, 2007; Parazzini et al, 1994; Tolstrup et al, 2003; Zhang & Bracken, 1996).…”

Section: Introductionmentioning

confidence: 99%

“…Studies evaluating alcohol consumption in continuous or discrete levels of intake have produced more mixed results(Andersen, et al, 2012; Armstrong, et al, 1992; Cavallo, et al, 1995; Chiodo, et al, 2012; Harlap & Shiono, 1980; Henriksen, et al, 2004; Kesmodel, et al, 2002; Kline, et al, 1980; Maconochie, et al, 2007; Parazzini, et al, 1994; Rasch, 2003; Windham, Fenster, & Swan, 1992; Windham, et al, 1997). Most research examining levels of alcohol use has found evidence of a threshold between two to four drinks per week at which alcohol use during pregnancy is related to miscarriage(Andersen, et al, 2012; Armstrong, et al, 1992; Harlap & Shiono, 1980; Henriksen, et al, 2004; Kesmodel, et al, 2002; Kline, et al, 1980; Maconochie, et al, 2007; Rasch, 2003; Windham, et al, 1992; Windham, et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

Volume and Type of Alcohol During Early Pregnancy and the Risk of Miscarriage

Avalos

Roberts

Kaskutas³

et al. 2014

Substance Use & Misuse

View full text Add to dashboard Cite

This study addresses the relationship between alcohol use during pregnancy and miscarriage. A cohort study of pregnant women (n=1061) recruited from 1996 –1998 in the San Francisco area. 3% (n=32) drank 4 or more drinks per week, 38% (n=403) consumed <4 drinks per week and 59% (n= 626) reported no alcohol intake. Women were also categorized by the type of alcohol consumed. An increased risk of miscarriage was found for 1) women who drank four or more drinks a week and 2) women who drank spirits. Future research assessing miscarriage risk should consider the volume and type of alcohol consumed.

show abstract

“…87,88 Excessive coffee consumption may also increase the risk of miscarriage. 89,90 It seems sensible to strongly recommend a healthy lifestyle and give advice regarding smoking, alcohol and caffeine consumption to couples with recurrent miscarriage.…”

Section: Lifestyle Factorsmentioning

confidence: 99%

Recurrent miscarriage

Horne

Alexander

2005

j fam plann reprod health care

View full text Add to dashboard Cite

Recurrent miscarriage, the occurrence of three consecutive first-trimester losses of pregnancy, affects 1% of women. The purported causes of recurrent miscarriage include chromosomal abnormalities, thrombophilia, metabolic disorders, anatomical causes and immune factors. At present, the only recommended investigations are testing for lupus anticoagulant and anticardiolipin antibody levels (to diagnose antiphospholipid syndrome, an acquired thrombophilia) and the karyotyping of both parents for chromosomal abnormalities. Women with antiphospholipid syndrome should be offered treatment with aspirin and low molecular weight heparin. Couples with chromosomal abnormalities should be referred to a clinical geneticist with whom the options of prenatal diagnosis, pre-implantation genetic diagnosis, donor gametes and adoption in subsequent pregnancies should be discussed. Couples with unexplained recurrent miscarriage should be offered appropriate emotional support and reassurance that they have a good prognosis for future pregnancies. increases to approximately 50% for women with three or more losses without a liveborn infant. 6,7 The purported causes of recurrent miscarriage include chromosomal anomalies, thrombophilia, metabolic disorders, anatomical causes and immune factors.

show abstract

Cigarette, alcohol, and caffeine consumption: risk factors for spontaneous abortion

Abstract: Consumption of 5 or more units alcohol per week and 375 mg or more caffeine per day during pregnancy may increase the risk of spontaneous abortion.

Cited by 239 publications

References 26 publications

Recurrent miscarriage: causes, evaluation and management

Recurrent miscarriage: causes, evaluation and management

Volume and Type of Alcohol During Early Pregnancy and the Risk of Miscarriage

Recurrent miscarriage

Contact Info

Product

Resources

About