Background:The open abdomen is a surgical technique used in the treatment of patients with abdominal sepsis, abdominal trauma, and abdominal hypertension syndrome. Objective: The aim was to demonstrate the effectiveness of a new surgical technique designed for the management and closure of the abdominal wall in patients with open abdomen. Method: The study of all patients treated with open abdomen in our hospital over a 5-year period. Results: It were included 24 patients, 18 men and 6 women. The average age was 41.5 ± 15.9 years. Operative diagnosis was abdominal compartment syndrome in 7 (29%) cases, abdominal sepsis in 9 (38%), and abdominal trauma in 8 (33%). The median of APACHE II score was eight points (range: 5-21), while the assessment of SIRS score had a median of two points (range: 1-4). The median of surgical procedures performed in operating room was two per patient. The median of fascial surgical closures performed in the patient bed was four. A successful closure of the abdominal wall was performed in 21 of 22 live patients (95%). Conclusions: The sequential closure of the abdominal wall is an effective technique that offers an alternative to the management of the open abdomen.