Cicatricial Alopecia of Sarcoidosis

Golitz, Loren E.

doi:10.1001/archderm.1973.01620200072021

Cited by 26 publications

(17 citation statements)

References 13 publications

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“…7.8). Golitz et al (1973) reported four patients, all black women, with sarcoidosis causing cicatricial alopecia, and reviewed 13 previously published cases. Other cases have been described by Brodkin (1969, Case 1) and Andersen (1977), who emphasized the difficulty 195 of differential diagnosis from necrobiosis lipoidica affecting the scalp.…”

Section: Alopeciamentioning

confidence: 99%

Sarcoidosis

Scadding

Mitchell

1985

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Section: Alopeciamentioning

confidence: 99%

Sarcoidosis

Scadding

Mitchell

1985

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“…However, this case is distinct from familial sarcoidosis as described by Blau (Blau's syndrome) which includes skin, ocular and joint involvement. However, we have identified 13 cases clinically similar to this in the literature including those described by Mehregan, Golitz, Andersen and Takahashi 4–7 . They all describe scarring alopecia with atrophy and many cases noted the similarity with necrobiosis lipoidica.…”

Section: Discussionmentioning

confidence: 60%

Case 1

Harman

Calonje²,

Robson³

et al. 2003

Clinical and Experimental Dermatology

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“…Although cutaneous involvement in sarcoidosis is relatively common, sarcoidosis of the scalp is rare. There are few reported cases of cicatricial alopecia due to sarcoidosis, which predominantly affects black women with evidence of intrathoracic sarcoidosis and cutaneous involvement at other sites 8–11 . Cases of nonscarring alopecia have also been reported, either with localized involvement or with total alopecia 9 .…”

Section: Discussionmentioning

confidence: 99%

Systemic sarcoidosis presenting with alopecia of the scalp

2004

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A 39‐year‐old African‐American woman was referred to the department of dermatology, Mount Sinal Hospital, New York for evaluation of a skin lesion on her scalp which had been present for 3 years and had recently changed in appearance. On examination, she was found to have erythematous plaques with hair loss extending from the frontal hairline on the right side in a “C‐shaped” distribution, terminating behind the left ear. Two years later the lesion had rapidly extended to the vertex of the scalp and left temporal area (Fig. 1). There was a 10 cm × 12 cm area of alopecia at the vertex with slight erythema, but there was no evidence of scarring, inflammation or nodularity of the scalp (Fig. 2). A skin biopsy taken from the forehead revealed granulomatous dermatitis showing noncaseating granuloma with negative acid fast bacilli (AFBC) and ammonical‐silverstain for fungus (GMS) (Fig. 3). 1 Erythematous plaque with hair loss on the left temporal area 2 Nonscarring alopecia at the vertex with slight erythema 3 Noncaseating granuloma consisting of lymphocytes, histiocytes, plasma cells and multinucleated giant cells (hematoxylin and eosin staining; magnification ×100) She complained of chronic nasal congestion for 8 months. Nasal cavity examination and laryngeal endoscopy showed multiple nodules on the nasal septum and vocal cord. At that time, a presumptive diagnosis of sarcoidal nodule of the nasal septum and vocal cord was made and corticosteroids were administered orally. A chest X‐ray demonstrated prominence of the right peritracheal and perihilar regions consistent with sarcoid. A 67 Gallium scan disclosed increased uptake in the lung and perihilar lymph nodes. A skull X‐ray showed soft tissue density of the skull, probably indicating a subcutaneous sarcoidal nodule. Computed tomography (CT) scanning of her brain and skull base showed a soft tissue mass along the outer table of the calvarium within the frontal region. Six years ago, she experienced visual changes: blurred vision, tearing, floaters on both eyes and a 1 cm × 1 cm subcutaneous, painful, firm mass on the lateral side of her left upper eyelid. A skin biopsy was performed in another hospital and revealed noncaseating granuloma. A diagnosis of sarcoidosis involving the central nervous system, lacrimal gland, nasal septum, vocal cord, lung and scalp was made, and the patient was treated with 20 mg of methylprednisone on alternate days with intralesional triamcinolone injection for skin lesions. During the follow‐up period, nasal, laryngeal, pulmonary, ocular and cutaneous lesions were slightly improved and magnetic resonance imaging (MRI) scanning will be carried out for further evaluation of the brain lesion.

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Cicatricial Alopecia of Sarcoidosis

Cited by 26 publications

References 13 publications

Sarcoidosis

Sarcoidosis

Case 1

Systemic sarcoidosis presenting with alopecia of the scalp

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