2013
DOI: 10.11622/smedj.2013018
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Churg-Strauss syndrome presenting with focal segmental glomerulosclerosis without proteinuria: response to unconventional therapy

Abstract: Churg-Strauss syndrome (CSS), or allergic granulomatosis, is a rare disease manifested by tissue infiltration, hypereosinophilia and vasculitis. Renal involvement may be seen in up to 50% of cases. We report the case of a 25-yearold man who presented with a history of fever for two months, tingling, numbness, and paraesthesia of the upper limbs and left lower limb, along with diarrhoea for one month and an inability to walk for the past seven days. Serial laboratory investigations helped to reach the final dia… Show more

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“…Diabetes mellitus has been found in about 37–40% of patient with AG, and may be caused by injury of elastic fiber from hyperglycemic state [ 12 ]. As for the renal condition, focal segmental glomerulosclerosis has been described in association with various granulomatous diseases (e.g., sarcoidosis, Wegener's granulomatosis, Churg-Strauss syndrome, and Kimura's disease) [ 13 , 14 , 15 , 16 ]. However, the association of AG and focal segmental glomerulosclerosis has never been reported.…”
Section: Discussionmentioning
confidence: 99%
“…Diabetes mellitus has been found in about 37–40% of patient with AG, and may be caused by injury of elastic fiber from hyperglycemic state [ 12 ]. As for the renal condition, focal segmental glomerulosclerosis has been described in association with various granulomatous diseases (e.g., sarcoidosis, Wegener's granulomatosis, Churg-Strauss syndrome, and Kimura's disease) [ 13 , 14 , 15 , 16 ]. However, the association of AG and focal segmental glomerulosclerosis has never been reported.…”
Section: Discussionmentioning
confidence: 99%