Chrysoidine-Dyed Bait: A Possible Carcinogenic Hazard to Anglers?

Coarse fishing and urothelial cancer: a regional case–control study

“…The most likely explanation for the results of this study being different from those of our earlier study (Sole & Sorahan, 1985) is chance, although alternative explanations are possible. The chrysoidine dyes are impure and their mutagenicity varies widely (Sole & Chipman, 1986), and it is possible that our earlier findings reflected a time when fishermen in the West Midlands were exposed to a highly mutagenic variety.…”

“…The chrysoidine dyes are impure and their mutagenicity varies widely (Sole & Chipman, 1986), and it is possible that our earlier findings reflected a time when fishermen in the West Midlands were exposed to a highly mutagenic variety.…”

“…Chrysoidine, a low molecular weight mono-azo-dye has been found in the urine of men working in the paper dyeing industry (Lowery et al, 1980). Two case-control studies have provided information on the topic of whether the use of dyed maggots by anglers leads to an increased risk of developing urothelial cancers (Cartwright et al, 1983;Sole & Sorahan, 1985). One study (Cartwright et al, 1983) provided a null result, whereas the other (Sole & Sorahan, 1985) found an excess risk associated with the use of bronze maggots for more than 5 years.…”

“…Two case-control studies have provided information on the topic of whether the use of dyed maggots by anglers leads to an increased risk of developing urothelial cancers (Cartwright et al, 1983;Sole & Sorahan, 1985). One study (Cartwright et al, 1983) provided a null result, whereas the other (Sole & Sorahan, 1985) found an excess risk associated with the use of bronze maggots for more than 5 years. An IARC working group on the evaluation of carcinogenic risks recently concluded that, for chrysoidine, the evidence for carcinogenicity to humans was inadequate and that the evidence for carcinogencity to animals was limited (IARC, 1987).…”

“…An IARC working group on the evaluation of carcinogenic risks recently concluded that, for chrysoidine, the evidence for carcinogenicity to humans was inadequate and that the evidence for carcinogencity to animals was limited (IARC, 1987). Chrysoidine dyes have been found to be mutagenic in the Ames test (Sole & Chipman, 1986 All subjects in these two groups were sent a simple onepage postal questionnaire requiring yes/no answers on five occupations, four sports and three types of tobacco usage (see Table III). Information on racial origin was also requested (white (or Caucasian), black, Asian, or other).…”