Chryseobacterium (Flavobacterium) meningosepticum outbreak associated with colonization of water taps in a neonatal intensive care unit

Hoque, Selina; Graham, Janet; Kaufmann, Mary E.; Tabaqchali, Soad

doi:10.1053/jhin.2000.0908

Cited by 131 publications

(91 citation statements)

References 7 publications

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“…Most reported outbreaks among neonates have lasted a few weeks to a few months [5,8]. However, in one outbreak, the same strain of E. meningoseptica was isolated from eight babies over almost two years though most cases were asymptomatic [4]. It has been suggested that outbreaks caused by environmental contamination tend to be intermittent [9].…”

Section: Discussionmentioning

confidence: 99%

“…Thus transmission may have occurred throughout the 16-month period with several neonates becoming colonized without developing any symptoms. Indeed, in some previously reported outbreaks, asymptomatic cases were detected and did not require treatment [4,8]. We screened asymptomatic babies at one point in time and we identified two neonates who were colonized with E. meningoseptica but remained well without antimicrobial treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Many cases of E. meningoseptica infections have been reported as part of outbreaks which have been attributed to contamination of hospital tap-water, disinfectants, saline, antibiotic solutions, lipid solution, sink drains and respiratory equipment [1,4,5]. In most reported outbreaks, the number of cases of neonatal meningitis was small and rarely exceeded five.…”

Section: Introductionmentioning

confidence: 99%

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An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius

Issack

Neetoo²

2011

J Infect Dev Ctries

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Introduction: Elizabethkingia meningoseptica is a rare but well-recognised cause of neonatal meningitis. Reported outbreaks have involved very few cases. We describe the management and outcome of a relatively large outbreak of E.meningoseptica neonatal meningitis Methodology: From August 2002 to December 2003, eight cases of meningitis caused by E. meningoseptica occurred among babies admitted to the neonatal ward of Jawarhlal Nehru hospital, Mauritius. In all cases, the organism was isolated from the cerebrospinal fluid. Infection control measures were re-emphasized after each case and environmental swabs were cultured on several occasions. Results: The affected babies were aged 6 to 20 days (mean age of 10 days). Seven of the babies weighed < 2,500 g. All CSF isolates had the same antibiotic susceptibility pattern. Apart from one baby who died shortly after admission, all cases responded to treatment with intravenous piperacillin and oral rifampicin for three weeks. Hydrocephalus developed in two babies and was subsequently fatal in one case. At follow-up of the other cases, one baby had severe neurological sequelae but a full recovery was observed in the other four cases. The source of the outbreak could not be established conclusively. Conclusions: The outcome was better than what has been reported in the medical literature. Prompt identification of the causative organism and initiation of appropriate antimicrobial therapy is essential. The combination of piperacillin and rifampicin should be considered an option for the treatment of E. meningoseptica neonatal meningitis if supported by properly performed antibiotic susceptibility test results.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius

Issack

Neetoo²

2011

J Infect Dev Ctries

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“…It rarely causes infection in the postneonatal immunocompetent host [7]. Intermittent epidemics in neonatal intensive care units (NICU) have been reported [8]; however, the exact source of these infections is often not elucidated. Environmental studies have shown that this organism can survive in chlorine-treated water, often colonizing sink basins and taps and in ventilator tubing [3,4].…”

Section: Discussionmentioning

confidence: 99%

Neonatal meningitis caused by Elizabethkingia meningoseptica in Saudi Arabia

Amer

Bandey

Bukhari³

et al. 2011

J Infect Dev Ctries

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Elizabethkingia meningoseptica is a multi-drug resistant organism that can cause meningitis in premature neonates. We report a case of Elizabethkingia meningoseptica meningitis that was detected early in an extremely premature low birth weight infant. He was successfully treated with a combination of ciprofloxacin and piperacillin-tazobactam. The spread of infection was controlled with no other reported cases.

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“…It is widely distributed in different geographical areas and habitats, but not in human microflora. 1 We describe the first clinical case of corneal ulcer caused by E. meningoseptica registered in Europe.…”

Section: Introductionmentioning

confidence: 98%

Elizabethkingia meningoseptica and Contact Lens Use

Beato¹,

Espinar²,

Figueira³

et al. 2016

Acta Med Port

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RESUMODoente de 47 anos, sexo masculino, recorreu ao serviço de urgência por início súbito de dor ocular e hiperemia conjuntival no olho esquerdo. Os antecedentes oftalmológicos incluíam o uso de lente de contacto semi-rígida e glaucoma primário de ângulo aberto. O exame na lâmpada de fenda revelou uma pequena úlcera de córnea central associada a infiltrado inflamatório estromal. A zaragatoa da base da úlcera de córnea permitiu a identificação de colónias de Elizabethkingia meningoseptica. O doente foi empiricamente tratado com levofloxacina colírio 0,5% e pomada de gentamicina 0,3%, tendo a infecção resolvido após cinco semanas. CASE REPORTA 47-year-old caucasian man presented to the ophthalmology emergency department of the Centro Hospitalar São João (Porto, Portugal) in August 2013 with a two day history of increasing pain and redness of his left eye (OS). He had no relevant systemic antecedents but he was regularly followed in the outpatient department due to primary open-angle glaucoma (treated with topical latanoprost, brimonidine, timolol and brinzolamide) and pathological myopia. Right eye visual acuity (VA) was hand movement due to terminal glaucoma. Ophthalmological antecedents also included the use of semi-rigid contact lens in the left eye. On our first examination, left eye visual acuity was 20/32 and biomicroscopy revealed a stromal keratitis with ill-defined borders and a small epithelial defect measuring 0.5 mm x 0.5 mm (Fig. 1). Scrapings from corneal ulcer and lower conjunctival fornix were sent for microbiological testing and topical empiric treatment (0,5% levofloxacin drops 1/1 hour and 0,3% gentamicin ointment 4/4 hours for 3 days) was prescribed. Evaluation 72 hours later showed loose re-epithelialization of the ulcer and ABSTRACTA 47-year-old man presented to our emergency department complaining of acute ocular pain and redness of his left eye. Ophthalmological antecedents included use of semi-rigid contact lens and primary open-angle glaucoma. Slit-lamp examination revealed a small central corneal ulcer associated with stromal inflammatory infiltrate. Scraping from the corneal ulcer was positive for Elizabethkingia meningoseptica. He was empirically treated with topical 0.5% levofloxacin and 0.3% gentamicin, and five weeks later the infection had resolved. In this case report we describe the uncommon association between contact lens and Elizabethkingia meningoseptica. Despite possible serious complications associated with this atypical agent, prompt diagnosis and adequate treatment lead to good visual prognosis.

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Chryseobacterium (Flavobacterium) meningosepticum outbreak associated with colonization of water taps in a neonatal intensive care unit

Cited by 131 publications

References 7 publications

An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius

An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius

Neonatal meningitis caused by Elizabethkingia meningoseptica in Saudi Arabia

Elizabethkingia meningoseptica and Contact Lens Use

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