Chronology and sequence of deciduous teeth eruption in children with microcephaly associated to the Zika virus

Abstract

IntroductionDeciduous teeth eruption is connected to children's growth and development. In Brazil, with the increase in the occurrence of children born with microcephaly associated to exposure to Zika virus, studies about orofacial alterations were necessary.ObjectiveDescribe the chronology and sequence of deciduous teeth in children with microcephaly due to the fetal exposure to Zika virus.MethodologyA cross‐sectional study involving 74 children of a neuropediatric reference unit in Salvador, Bahia, in 2017 was conducted. Through use of secondary data, interviews with mothers and children's exam, the population was characterized, the chronology and sequence of deciduous teeth eruption was registered, and the analysis of the variables was proceeded.ResultsThe first eruption happened between 4 and 17 months of age and 52.70% had a delay in the eruption of incisors. The average eruption time for the maxilla varies from 17.92 (16.56‐19.28; 95% CI) to 20.43 (19.35‐21.51; 95% CI) months, and the jaw from 11.57 (6.85‐18.99; 95% CI) to 20.20 (19.09‐21.31; 95% CI) months. In 77.94% of population, the eruption of the first teeth was in the lower arch and in 33.82%, molars and/or canines erupted before the incisors.ConclusionsThere were alteration in the chronology and sequence of deciduous teeth eruption.

Developmental enamel defects and other oral problems in children with microcephaly associate with fetal exposure to zika virus (ZIKV)

“…However, studies focusing on this issue are still scarce in the literature. [4][5][6][7][8] As a result, the possibilities of interation with the literature are limited, making it often necessary to discuss the results from data observed in child. 23 Thus, unlike studies that analyzed a similar age range in the general population, [24][25][26][27] the occurrence of dental caries was not observed in this study.…”

“…2 Some clinical findings in children with microcephaly associated with ZIKV have already been published, such as brain changes, neurological abnormalities, 3 bone and craniofacial deformities. [4][5][6][7][8] Changes have also been reported in children with microcephaly caused by other causes, for example, impaired vision and hearing, delayed cognitive, motor and speech development 8,9 and epilepsy. 10 However, there are few studies describing the types and severity of oral changes in children with microcephaly associated with ZIKV.…”

“…10 However, there are few studies describing the types and severity of oral changes in children with microcephaly associated with ZIKV. There are reports of the occurrence of tooth eruption delay and changes in the eruption sequence 6,8 lip hypotonia, absence of lip sealing and mouth breathing 3 and enamel opacity. 5,8 Carvalho et al, 11 described that, in a population of 30 children with this condition, 20% had inadequate tongue position at rest and also registered the presence of short labial or lingual curb, micrognathia, changes in the shape or number of teeth and spasms muscle.In addition to bone development, systemic, local or hereditary disorders that occur during enamel development can cause anomalies in its structure, affecting deciduous and / or permanent dentition [12][13][14] and these dental enamel development defects (DDE) predispose to a greater risk of dental caries.…”

Sequence and chronology of tooth eruption in children and adolescents from Santa Maria - southern Brazil

“…Besides sex, other factors can alter the eruption chronology, either delaying or accelerating the process, such as birth weight (VERMA et al, 2017), eating habits (HOLMAN & YAMAGUCHI, 2005;VERMA et al, 2017), nutrition (BASTOS et al, 2007HOLMAN & YAMAGUCHI, 2005), socioeconomic status (BASTOS et al, 2007;VERMA et al, 2017), body mass index (VERMA et al, 2017), heredity (HATTON, 1955), systemic and local diseases D'AGOSTINO et al, 2020;LIMA et al, 2019), and regionality (HOLMAN & YAMAGUCHI, 2005;VERMA et al, 2017). Thus, it is observed that the variation in tooth eruption is multifactorial (VERMA et al, 2017).…”

Eruption cyst in a patient with microcephaly: a case report

“…Microcephaly is diagnosed after birth when the head circumference measures less than 32 cm -value considered ideal. 1,3 Patients with microcephaly may have multiple associated oral conditions, 5,6 including eruption cyst (EC), defined as a liquid cavity originating from dental epithelial tissues. 7 EC is a benign pathology, usually asymptomatic, that happens in a retained, impacted, non-erupted tooth or a tooth with late eruption, adjacent to the dental crown at the cementoenamel junction.…”