Chronological Changes in Ropivacaine Concentration and Analgesic Effects Between Transversus Abdominis Plane Block and Rectus Sheath Block

Murouchi, Takeshi; Iwasaki, Sohshi; Yamakage, Michiaki

doi:10.1097/aap.0000000000000288

Cited by 36 publications

(28 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies on the rise in plasma ropivacaine concentration reported that Tmax was 23.1 min and 48.5 min after TAP block and rectus sheath block , respectively. Similarly, another study reported that Tmax of ropivacaine was 35 min and 53 min after TAP and rectus sheath block, respectively. These reports showed that the Tmax after rectus sheath block took approximately twice as long as the Tmax after TAP block, which is similar to the results we observed with levobupivacaine.…”

Section: Discussionmentioning

confidence: 78%

A comparison of plasma levobupivacaine concentrations following transversus abdominis plane block and rectus sheath block

2016

View full text Add to dashboard Cite

SummaryLevobupivacaine is commonly used as the local anaesthetic of choice in peripheral nerve blocks, but its pharmacokinetics have not been fully investigated. We compared the changes in plasma concentrations of levobupivacaine following transversus abdominis plane block and rectus sheath block. Fifty woman undergoing laparoscopy were randomly allocated to receive either a transversus abdominis plane block or an rectus sheath block. In both groups, 2.5 mg.kg À1 levobupivacaine was administered, and blood samples were obtained 15 min, 30 min, 60 min and 120 min after injection. The mean maximum plasma concentration (Cmax) and mean time to reach Cmax (Tmax) as determined by non-linear regression analysis were 1.05 lg.ml À1 and 32.4 min in the transversus abdominis plane group and 0.95 lg.ml À1 and 60.9 min in the rectus sheath group, respectively. The plasma concentration of levobupivacaine peaked earlier in the transversus abdominis plane group than in the rectus sheath group and the maximum plasma concentration depended on the dose administered but not the procedure.

show abstract

Section: Discussionmentioning

confidence: 78%

A comparison of plasma levobupivacaine concentrations following transversus abdominis plane block and rectus sheath block

2016

View full text Add to dashboard Cite

show abstract

“…The effects of abdominal truncal blocks, such as TAPBs and rectus sheath block, are relatively short. 3,7 The exception is PVB, the analgesic effect of which can last for 24 hours with long-acting local anesthetics. 8 Although QLB was reportedly effective against abdominal somatic pain, 9 the duration of the block had been unknown.…”

Section: Discussionmentioning

confidence: 99%

Quadratus Lumborum Block

Murouchi

Iwasaki

Yamakage

2016

Regional Anesthesia and Pain Medicine

Self Cite

178

View full text Add to dashboard Cite

show abstract

“…Although pain scores and overall opioid consumption may be reduced in some settings for up to 24 to 48 hours, 77,91 when block duration is measured by offset of sensory block or time to first request for rescue analgesia, volunteer and clinical studies of both landmark-guided 77,90,91 and US-guided approaches 13,28,121,122 indicate that this ranges from 6 to 10 hours on average with bupivacaine or ropivacaine. Although this can be overcome by placement of catheters in the TAP plane, either percutaneously or surgically, there are several issues to be considered.…”

Section: Single-shot Versus Continuous Tap Blockmentioning

confidence: 99%

“…Patients should also be closely monitored for at least 30 to 45 minutes because this is the average time to peak plasma concentration following truncal blocks. 22,49,122,132,136,173,272 …”

Section: Local Anesthetic Systemic Toxicitymentioning

confidence: 99%

Essentials of Our Current Understanding

Chin

McDonnell

Carvalho

et al. 2017

Regional Anesthesia and Pain Medicine

346

208

View full text Add to dashboard Cite

Abdominal wall blocks rely on the spread of local anesthetic within musculofascial planes to anesthetize multiple small nerves or plexuses, rather than targeting specific nerve structures. Ultrasonography is primarily responsible for the widespread adoption of techniques including transversus abdominis plane and rectus sheath blocks, as well as the introduction of novel techniques such as quadratus lumborum and transversalis fascia blocks. These blocks are technically straightforward and relatively safe and reduce pain and opioid requirements in many clinical settings. The data supporting these outcomes, however, can be inconsistent because of heterogeneity of study design. The extent of sensory blockade is also somewhat variable, because it depends on the achieved spread of local anesthetic and the anatomical course of the nerves being targeted. The blocks mainly provide somatic analgesia and are best used as part of a multimodal analgesic regimen. This review summarizes the anatomical, sonographic, and technical aspects of the abdominal wall blocks in current use, examining the current evidence for the efficacy and safety of each.

show abstract

Chronological Changes in Ropivacaine Concentration and Analgesic Effects Between Transversus Abdominis Plane Block and Rectus Sheath Block

Cited by 36 publications

References 21 publications

A comparison of plasma levobupivacaine concentrations following transversus abdominis plane block and rectus sheath block

A comparison of plasma levobupivacaine concentrations following transversus abdominis plane block and rectus sheath block

Quadratus Lumborum Block

Essentials of Our Current Understanding

Contact Info

Product

Resources

About