Chronological Aging in African-American Skin: A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors

Chien, Anna L.; Qi, Ji; Grandhi, Radhika; Harris-Tryon, Tamia; Kim, Noori; Jang, Min Soo; Olowoyeye, Omolara; Kuhn, Diane; Leung, Sherry; Rainer, Barbara M.; Poon, Flora; César, Sabrina Sisto Alessi; Suh, Jean; Cheng, Nancy; Okoye, Ginette A.; Kang, Sewon

doi:10.1016/j.jnma.2018.01.005

Cited by 4 publications

(8 citation statements)

References 15 publications

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“…In highly pigmented skin, aging at photoexposed sites appears to manifest at a significantly slower rate and with less coarse wrinkling and laxity than is apparent in lightly pigmented skin (Chien et al, 2018b). However, skin changes that manifest at photoprotected sites, such as buttock and upper inner arm, appear to be similar between individuals regardless of skin pigmentation (Chien et al, 2018a).…”

Section: Introductionmentioning

confidence: 99%

Aging in Skin of Color: Disruption to Elastic Fiber Organization Is Detrimental to Skin’s Biomechanical Function

Langton

Alessi

Hann

et al. 2019

Journal of Investigative Dermatology

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Skin aging is a complex process involving the additive effects of time-dependent intrinsic aging and changes elicited via skin's interaction with the environment. Maintaining optimal skin function is essential for healthy aging across global populations; yet most research focuses on lightly pigmented skin (Fitzpatrick phototypes IeIII), with little emphasis on skin of color (Fitzpatrick phototypes VeVI). Here, we explore the biomechanical and histologic consequences of aging in black African-American volunteers. We found that healthy young buttock and dorsal forearm skin was biomechanically resilient, highly elastic, and characterized histologically by strong interdigitation of rete ridges, abundant organized fibrillar collagen, and plentiful arrays of elastic fibers. In contrast, intrinsically aged buttock skin was significantly less resilient, less elastic, and was accompanied by effacement of rete ridges with reduced deposition of both elastic fibers and fibrillar collagens. In chronically photoexposed dorsal forearm, significant impairment of all biomechanical functions was identified, with complete flattening of rete ridges and marked depletion of elastic fibers and fibrillar collagens. We conclude that in skin of color, both intrinsic aging and photoaging significantly impact skin function and composition, despite the additional photoprotective properties of increased melanin. Improved public health advice regarding the consequences of chronic photoexposure and the importance of multimodal photoprotection use for all is of global significance.

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Section: Introductionmentioning

confidence: 99%

Aging in Skin of Color: Disruption to Elastic Fiber Organization Is Detrimental to Skin’s Biomechanical Function

Langton

Alessi

Hann

et al. 2019

Journal of Investigative Dermatology

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“…The interest of using standard photographic scales to bring reliability and robustness in clinical evaluation of darkest skin tones was previously discussed 22–24 . Table 3 illustrates the 15 facial signs (definitions and respective scoring ranges) that were further analyzed by the AI‐based automatic grading system.…”

Section: Methodsmentioning

confidence: 99%

Objective and automatic grading system of facial signs from selfie pictures of South African women: Characterization of changes with age and sun‐exposures

Flament

Zhang²,

Jiang³

et al. 2022

Skin Research and Technology

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Objective To evaluate the capacity of the automatic detection system to accurately grade, from smartphones’ selfie pictures, the severity of fifteen facial signs in South African women and their changes related to age and sun‐exposure habits. Methods A two‐steps approach was conducted based on self‐taken selfie images. At first, to assess on 306 South African women (20–69 years) enrolled in Pretoria area (25.74°S, 28.22°E), age changes on fifteen facial signs measured by an artificial intelligence (AI)‐based automatic grading system previously validated by experts/dermatologists. Second, as these South African panelists were recruited according to their usual behavior toward sun‐exposure, that is, nonsun‐phobic (NSP, N = 151) and sun‐phobic (SP, N = 155) and through their regular and early use of a photo‐protective product, to characterize the facial photo‐damages. Results (1) The automatic scores showed significant changes with age, by decade, of sagging and wrinkles/texture (p < 0.05) after 20 and 30 years, respectively. Pigmentation cluster scores presented no significant changes with age whereas cheek skin pores enlarged at a low extent with two plateaus at thirties and fifties. (2) After 60 years, a significantly increased severity of wrinkles/texture and sagging was observed in NSP versus SP women (p < 0.05). A trend of an increased pigmentation of the eye contour (p = 0.06) was observed after 50 years. Conclusion This work illustrates specific impacts of aging and sun‐exposures on facial signs of South African women, when compared to previous experiments conducted in Europe or East Asia. Results significantly confirm the importance of sun‐avoidance coupled with photo‐protective measures to avoid long‐term skin damages. In inclusive epidemiological studies that aim at investigating large human panels in very different contexts, the AI‐based system offers a fast, affordable and confidential approach in the detection and quantification of facial signs and their dependency with ages, environments, and lifestyles.

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“…De las más de cien escalas 2 desarrolladas en la actualidad, en la Tabla 1 se describen las principales, las más empleadas en la práctica clínica habitual, 7,8 aquellas 9-13 con excelente validez de contenido, estructura interna y confiabilidad, de acuerdo con los estándares basados en el consenso para la selección 14 y algunas otras recientemente descritas que evalúan zonas específicas. [15][16][17][18][19][20][21][22][23][24][25][26] La principal región anatómica que toman en cuenta estas escalas se concentra en la cara, dividiéndola para su análisis en tercio superior, 20,27 tercio medio 20,28,29 y tercio inferior. 15,20 Un pequeño número de escalas se limitan al cuello, 30 tórax anterior 23,31 y extremidades superiores.…”

Section: Escalas Clínicas Para Evaluar El Envejecimiento De La Pielunclassified

“…15,20 Un pequeño número de escalas se limitan al cuello, 30 tórax anterior 23,31 y extremidades superiores. 17,19,25,32 La Figura 1 muestra las principales zonas evaluadas en cara por las diferentes escalas clínicas.…”

Section: Escalas Clínicas Para Evaluar El Envejecimiento De La Pielunclassified

“…Se han elaborado unas cuantas escalas para calificar zonas especiales que miden la disminución del tejido graso y la laxitud de los tejidos blandos (flacidez), como en el cuello. 30 Existen otras que analizan la severidad de las arrugas en el tórax anterior, tanto en reposo como en movimiento, 31 así como la presencia de manchas hiperpigmentadas, 21 algunas otras examinan datos de envejecimiento intrínseco en piel no fotoexpuesta de antebrazos: 25 flacidez, líneas finas, xerosis y adelgazamiento de la piel; otras más el fotoenvejecimiento en brazos (arrugas, elastosis solar, lentigos solares, Tabla 2: Principales escalas con validez de contenido, estructura interna y adecuadas pruebas de hipótesis que evalúan el envejecimiento cutáneo.…”

Section: Evaluación Del Envejecimiento De La Piel Extrafacialunclassified

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Escalas clínicas para evaluar el envejecimiento cutáneo: una revisión de la literatura

Ramírez¹,

Sánchez²,

Cruz³

et al. 2021

Revista Del Centro Dermatológico Pascua

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The present work is a current review of the different clinical scales used to evaluate skin aging, a process that is taken with little relevance in the medical field, but that has a significant impact on the quality of life of each patient, besides being one of the main factors that increase the susceptibility for the development of skin cancer. Due to the above described, we suggest to carry out an accurate detection of skin aging individually, to provide the appropriate treatment, improve the prognosis of the pathology, and reduce its progression or complications. This objective is largely limited by the use of scales that do not allow an evaluation of the therapeutic response in routine clinical practice, in addition to the subjective rating issued by the physician and the patient. The objective of this work was to carry out a review of the existing literature on the clinical scales used for the evaluation of skin aging, beginning with its description, its characteristics and clinical importance. Subsequently, the different diagnostic and evaluation scales of the therapeutic response are described, with which a comprehensive analysis can be carried out. The usefulness of the use of dermoscopy and its contribution to said evaluation as a complementary method in the aforementioned assessment is pointed out, and at the end, an evaluation algorithm is proposed in the Mexican population.

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Chronological Aging in African-American Skin: A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors

Cited by 4 publications

References 15 publications

Aging in Skin of Color: Disruption to Elastic Fiber Organization Is Detrimental to Skin’s Biomechanical Function

Aging in Skin of Color: Disruption to Elastic Fiber Organization Is Detrimental to Skin’s Biomechanical Function

Objective and automatic grading system of facial signs from selfie pictures of South African women: Characterization of changes with age and sun‐exposures

Escalas clínicas para evaluar el envejecimiento cutáneo: una revisión de la literatura

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