Chrono-exercise: Time-of-day-dependent physiological responses to exercise

Kim, Hyeon-Ki; Radák, Zsolt; Takahashi, Masaki; Inami, Takayuki; Shibata, Shigenobu

doi:10.1016/j.smhs.2022.11.003

Cited by 8 publications

(6 citation statements)

References 109 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Light is a central zeitgeber (“time giver”) for entraining the circadian clock to its external environment (Lorber et al, 2022 ). Besides light, physical exercise (Kim et al, 2023 ), and food (Lewis et al, 2020 ) for example, may serve as zeitgebers. Physiological and organ functions are thus, via the clock, also entrained to the normal daily cycles of life on Earth.…”

Section: A Link Between the Circadian Clock And Agingmentioning

confidence: 99%

Circadian regulation in aging: Implications for spaceflight and life on earth

et al. 2023

View full text Add to dashboard Cite

Alterations in the circadian system are characteristic of aging on Earth. With the decline in physiological processes due to aging, several health concerns including vision loss, cardiovascular disorders, cognitive impairments, and muscle mass loss arise in elderly populations. Similar health risks are reported as “red flag” risks among astronauts during and after a long‐term Space exploration journey. However, little is known about the common molecular alterations underlying terrestrial aging and space‐related aging in astronauts, and controversial conclusions have been recently reported. In light of the regulatory role of the circadian clock in the maintenance of human health, we review here the overlapping role of the circadian clock both on aging on Earth and spaceflight with a focus on the four most affected systems: visual, cardiovascular, central nervous, and musculoskeletal systems. In this review, we briefly introduce the regulatory role of the circadian clock in specific cellular processes followed by alterations in those processes due to aging. We next summarize the known molecular alterations associated with spaceflight, highlighting involved clock‐regulated genes in space flown Drosophila, nematodes, small mammals, and astronauts. Finally, we discuss common genes that are altered in terms of their expression due to aging on Earth and spaceflight. Altogether, the data elaborated in this review strengthen our hypothesis regarding the timely need to include circadian dysregulation as an emerging hallmark of aging on Earth and beyond.

show abstract

Section: A Link Between the Circadian Clock And Agingmentioning

confidence: 99%

Circadian regulation in aging: Implications for spaceflight and life on earth

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Current National Health Service guidelines specify ‘at least 150 min of moderate aerobic activity or 75 min of vigorous aerobic activity per week’. There is a linear relationship between energy expenditure and exercise intensity ( Kim et al, 2023 ). People need to exercise about twice as long at light- moderate intensity to burn the same number of calories as at very intense intensity ( Kim et al, 2023 ).…”

Section: Physical Activity To Prevent Metabolic Dysregulationmentioning

confidence: 99%

“…There is a linear relationship between energy expenditure and exercise intensity ( Kim et al, 2023 ). People need to exercise about twice as long at light- moderate intensity to burn the same number of calories as at very intense intensity ( Kim et al, 2023 ). The enhancing activity helps regulate blood sugar and fatty acid oxidation.…”

Section: Physical Activity To Prevent Metabolic Dysregulationmentioning

confidence: 99%

The effects of physical exercise therapy on weight control: its regulation of adipocyte physiology and metabolic capacity

Park¹,

Rhie²,

Shim³

2023

J Exerc Rehabil

View full text Add to dashboard Cite

Factors associated with increased body mass, including dyslipidemia, hypertension, insulin resistance, vascular endothelial dysfunction and sleep disorders, may contribute to the exacerbation of cardiovascular disease. These health problems associated with obesity are caused by accumulated metabolism and physical and emotional stress. Lifestyle, especially exercise, is a major therapeutic strategy for the treatment and management of obesity-induced metabolic problems. Metabolic disease often co-occurs with abdominal obesity. Exercise is necessary for the treatment of obesity, diabetes and cardiovascular disease. A potential benefit of exercise is to promote fat burning and energy use increases both during exercise itself and in the post-exercise period. Exercise suppresses basal metabolic rate and also has many health benefits. Why should we exercise to lose weight? Does physical activity help lower blood pressure, blood cholesterol, and blood sugar? In this article, we review the positive effects of physical exercise on weight maintenance and weight loss, and the effectiveness of physical exercise on the treatment and prevention of metabolic syndrome.

show abstract

“…Exercise has many health benefits, such as reducing the incidence and severity of metabolic diseases and increasing healthy life expectancy because it can provide many metabolic benefits through the liver, adipose tissue, and pancreas (Kim et al, 2022;Mode et al, 2023) However, excessive exercise activity can disrupt the production of free radicals and antioxidants, which is known as oxidative stress (Yunus, 2020). Someone who exercises in the right way, like by increasing the intensity of the exercise and choosing the right time to exercise, will get maximum benefits.…”

Section: Introductionmentioning

confidence: 99%

Dynamic levels of hormonal, oxidants, insomnia, and stress in badminton athletes who practice morning and evening

Ariyandy,

Arsyad,

Hasyar

et al. 2024

J. Hum. Sport Exerc.

View full text Add to dashboard Cite

Circadian rhythms are internal mechanisms that regulate various aspects of the human body's physiology and behaviour that are influenced by activity, physicality, and change time in 24 hours. This study aims to compare oxidant levels and hormonal levels based on differences in training times, namely morning and evening, in badminton athletes. This research involved 44 badminton athletes using a purposive sampling technique who were divided into a morning group (n = 22) and an evening group (n = 22). Melatonin levels were measured using the Elabscience Kit (No. E-EL-H2016) and malondialdehyde (MDA) levels using spectrophotometry. All research procedures have received ethical approval from the Hasanuddin University Medical Faculty Ethics Commission (Number: 377/UN4.6.4.5.31/PP36/2023). The results of this study indicate that the athlete's melatonin value in the morning was 76.71 ± (29.05-247.45) higher than in the evening 80.43 ± (50.83-155.24) Meanwhile, the athlete's MDA value in the evening was 2.08 ± (0.74–4.57) higher compared to the MDA in the morning of 1.09 ± (0.33–3.71). Meanwhile, based on the insomnia value for evening training, a higher value was obtained compared to morning training, namely 9.50 ± (3-11). However, there was no significant difference in stress levels. The results of the study showed that badminton athletes who trained at night tended to experience sleep disturbances (insomnia) and increased oxidant levels, while hormonal levels, especially melatonin, were higher in athletes who trained in the morning.

show abstract

Chrono-exercise: Time-of-day-dependent physiological responses to exercise

Cited by 8 publications

References 109 publications

Circadian regulation in aging: Implications for spaceflight and life on earth

Circadian regulation in aging: Implications for spaceflight and life on earth

The effects of physical exercise therapy on weight control: its regulation of adipocyte physiology and metabolic capacity

Dynamic levels of hormonal, oxidants, insomnia, and stress in badminton athletes who practice morning and evening

Contact Info

Product

Resources

About