Chronic wound-dressing chitosan-polyphenolic patch for pH responsive local antibacterial activity

Dielectric properties of chitosan and two ionic derivatives: Effect of counter anions

“…It can be seen that all the thermograms display two prominent peaks. The endothermic peaks observed between 70 and 90 °C can be associated to the loss of water (Chowdhury et al, 2022). The exothermic peaks at 295 °C for neat chitosan, 331…”

pH-Responsive wound dressings: advances and prospects

“…pH-Responsive hydrogels are the main type of pH-responsive wound dressings. Other advanced pH-responsive materials include nanofibers, 96 composite films, 97 nanoparticle clusters, 98 and microneedles, 99 each with unique characteristics and advantages for wound healing. In this section, the pH-responsive mechanisms and properties of other pH-responsive materials are discussed, and the relevant information is summarized in Table 2.…”

“…Its bacterial growth inhibition effect and pH-responsive drug release were demonstrated in vitro , and its antibacterial activity and drug release profiles were obtained. 97 Furthermore, CS can also be used as a surface modifier to prepare pH-responsive drug delivery system. 108…”

“…Its bacterial growth inhibition effect and pH-responsive drug release were demonstrated in vitro, and its antibacterial activity and drug release profiles were obtained. 97 Furthermore, CS can also be used as a surface modifier to prepare pH-responsive drug delivery system. 108 Besides hydrogels, nanofibers, and composite membrane materials, the field of pH-responsive wound dressings includes other materials, such as nanoparticle clusters, 98 microneedles, 118 sponges, 110,111 polysaccharide, 112 and foams, 113 which present specific designs and functions.…”

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

“…The resulting membrane yielded significantly reduced 20. 151 In a mild acidic environment, neomycin tends to release due to the increasing solubility of chitosan, whereas in a basic medium a sustained release profile of neomycin is observed because chitosan is not soluble, hence minimizing the tendency of neomycin to be released.…”