Chronic Vomiting Associated With a Gastric Carcinoid in a Cat

Abstract

A geriatric domestic shorthair cat was presented for evaluation of chronic vomiting. Chronic renal failure was diagnosed on the basis of physical examination findings and results of a serum biochemical profile and urinalysis. Endoscopically obtained gastric biopsies were suggestive of a carcinoid tumor. Subsequently, an exploratory celiotomy with partial gastrectomy was performed. Histopathological and electron microscopic analysis of surgical biopsy specimens confirmed the diagnosis of a gastric carcinoid, which has not been previously reported in the cat. Following complete excision, the cat remained clinically stable and free of signs of gastrointestinal disease for 4 months before requiring treatment for progressive renal failure.

Endocrine/Neuroendocrine System

“…Clinical signs generally reflect the anatomic location of the lesion. In one report, a cat with a 5-month history of vomiting was found with a stomach carcinoid (Rossmeisl et al, 2002). In one report, a cat with a 5-month history of vomiting was found with a stomach carcinoid (Rossmeisl et al, 2002).…”

“…16-26) (Choi et al, 2008;Ferreira et al, 2005;Saegusa et al, 1994), liver (Patnaik et al, 1981(Patnaik et al, , 2005a, gallbladder (Morrell et al, 2002), and skin (Konno et al, 1998;Joiner et al, 2010). In the cat, carcinoid tumors have been reported in the liver and gallbladder (Patnaik et al, 2005b), stomach (Rossmeisl et al, 2002), intestines (Slawienski et al, 1997), esophagus (Patnaik et al, 1990), tracheobronchus (Rossi et al, 2007), and skin (Patnaik et al, 2001). There appears to be no apparent sex or breed predilection.…”

Ultrasonografische en histopathologische bevindingen bij een uremische kat met maagadenocarcinoom

“…The stomach is the least frequently reported location. Only four cases of gastric adenocarcinoma have been reported in cats, representing only 1% of all reported gastrointestinal adenocarcinoma in this species (Turk et al, 1981;Rossmeisl et al, 2002;Dennis et al, 2006).…”

Immunohistochemical Characterization of a Hepatic Neuroendocrine Carcinoma in a Cat

“…12 Neuroendocrine carcinomas in pets tend to be locally invasive and metastasize in local lymph nodes, lung, pleura, pancreas, and peritoneal cavities. 14,15 Confirmation of a histopathologic diagnosis requires special stains to reveal argyrophilic properties, but those reactions may be negative, especially in rectal neuroendocrine carcinomas. 8 Immunohistochemical stains can be useful in confirming the diagnosis.…”

“…6 In domestic animals, they have been described mainly in dogs, but also in cats, horses, and cows, and involve the nasal cavity, nasopharynx, lungs, esophagus, stomach, intestine, liver, bile ducts, and gallbladder. 1,7,8,11,14 Neuroendocrine carcinomas of the liver, extra hepatic bile ducts, and gallbladder are rare neoplasms in cats. 10 Therefore, the prevalence of these tumors is not established, and there are no defined age, breed, or sex predilections.…”