Chronic Urticaria and Celiac Disease: A Case Report

Peroni, Diego; Paiola, Giulia; Tenero, Laura; Fornaro, M.; Bodini, Alessandro; Pollini, F; Piacentini, Giorgio

doi:10.1111/j.1525-1470.2009.01066.x

Cited by 17 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other reports associating chronic urticaria with coeliac disease in children have been found. The vast majority of these children had urticaria remission after a gluten-free diet (30)(31)(32). This finding is worthy of further investigation, since it might suggest screening for coeliac disease in children with chronic urticaria, especially in refractory cases.…”

Section: Other Autoimmune Conditionsmentioning

confidence: 87%

Management of Childhood Urticaria: Current Knowledge and Practical Recommendations

Pité¹,

Wedi²,

Borrego³

et al. 2013

Acta Derm Venerol

View full text Add to dashboard Cite

Urticaria, defined by the presence of wheals and/or angio-edema, is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identification of eliciting triggers and pharmacological therapy. This review systematically discusses the current best-available evidence on spontaneous acute and chronic urticaria as well as physical and other urticaria types in children. Potential underlying causes, namely infections, food and drug hypersensitivity, autoreactivity and autoimmune or other conditions, and eliciting stimuli are considered, with practical recommendations for specific diagnostic approaches. Second-generation antihistamines are the mainstay of pharmacological treatment aimed at relief of symptoms, which require dose adjustment for pae-diatric use. Other therapeutic interventions are also discussed. In addition, unmet needs are highlighted, aiming to promote research into the paediatric population, ultimately aiming at the effective management of childhood urticaria.

show abstract

Section: Other Autoimmune Conditionsmentioning

confidence: 87%

Management of Childhood Urticaria: Current Knowledge and Practical Recommendations

Pité¹,

Wedi²,

Borrego³

et al. 2013

Acta Derm Venerol

View full text Add to dashboard Cite

show abstract

“…Theoretically, this mechanism might cause urticarial lesions, so by restoring the integrity of the mucosa, a GFD might resolve them [ 101 ]. Furthermore, even though no meta-analysis is available, in some cases of CU, the adoption of a GFD has proven effective in controlling skin lesions in CD patients, further confirming that CU may be a cutaneous manifestation of CD and not a mere chance association [ 98 , 102 ]. Recently, Kolkhir et al stated that CU is strongly linked with various autoimmune diseases, such as Hashimoto’s thyroiditis, pernicious anemia, vitiligo, diabetes mellitus type 1, Grave’s disease, and rheumatoid arthritis, and that it is essential to test children with chronic spontaneous urticaria (CSU) for other autoimmune diseases, including CD [ 103 ].…”

Section: Chronic Urticariamentioning

confidence: 99%

Skin Manifestations and Coeliac Disease in Paediatric Population

et al. 2021

View full text Add to dashboard Cite

Celiac disease (CD) is an immune-mediated enteropathy caused by gluten ingestion, affecting approximately 1% of the worldwide population. Extraintestinal symptoms may be present as the first signs of CD, years before the CD diagnosis is made. A great variety of extraintestinal manifestations may be associated with CD. Cutaneous manifestations represent the main extraintestinal manifestations, with dermatitis herpetiformis being the most common in patients with CD. In adults, it has been demonstrated that the role of a gluten-free diet is crucial not only for the recovery of signs and symptoms associated with CD but also for cutaneous manifestations, which often improve after gluten avoidance. In children with CD, the association with skin disorders is well documented regarding dermatitis herpetiformis, but studies considering other dermatological conditions, such as psoriasis and atopic dermatitis, are few. The prevalence and manifestations of dermatological disorders in celiac children are often different from those in adults, explaining the gap between these populations. In addition, the therapeutic role of a gluten-free diet in the improvement in skin alterations is not fully understood in children and in adult population except for dermatitis herpetiformis. Therefore, cutaneous CD symptoms need to be known and recognized by physicians despite their specialties to improve early CD diagnosis, which is critical for a better prognosis. This review describes the current scientific evidence on skin manifestations associated with CD in the pediatric population.

show abstract

“…Celiac disease has been recently recognized as a systemic autoimmune comorbidity in a subset of CSU patients 23 . Anecdotal case reports have reported improvement of CSU after gluten‐free diet (GFD) in patients having concomitant celiac disease 24,25 …”

Section: Elimination Dietsmentioning

confidence: 99%

“…Dietary elimination of fish or fish products and mammalian meat or meat products has Grade B recommendation each, while dietary elimination of gluten has Grade C recommendation (Table 3 ) 16,17,19–22,24–41 . However, elimination diets may be tried in a subset of refractory CSU patients, for example, those with a history of anaphylaxis, resident of tick endemic areas for AGS, or confirmed coexistence of food allergy by a double‐blind placebo‐controlled food challenge, when benefits outweigh risks.…”

Section: Elimination Dietsmentioning

confidence: 99%

Dietary strategies for chronic spontaneous urticaria: an evidence‐based review

2021

View full text Add to dashboard Cite

Although the relationship between diet and chronic spontaneous urticaria (CSU) remains elusive, several patients seek dietary modifications as they are easy and cost-effective.Adequate patient education and counseling are crucial as modified diets may be beneficial for a subset of antihistamine refractory CSU patients, and no modality currently exists to identify these patients. Elimination of food items based exclusively on patient history may lead to unnecessary restrictions in most cases resulting in nutritional deficiencies and impaired quality of life. Several dietary strategies have been tried till date with varying rates of success and evidence. This review highlights the various dietary strategies along with their levels of evidence, which may help the treating dermatologists and physicians to counsel CSU patients and make evidence-based treatment decisions. There is grade A recommendation for the elimination of food additives (artificial pseudoallergens), personalized diets, vitamin D supplementation, Diamine oxidase supplementation and probiotics (in children), grade B recommendation for dietary elimination of red meat, fish and their products, natural pseudoallergens (fruits, vegetables, and spices), and lowhistamine diet, while dietary elimination of gluten (with concomitant celiac disease) has grade C recommendation. Notably, elimination diets should be continued for at least 3 consecutive weeks to assess their effectiveness.

show abstract

Chronic Urticaria and Celiac Disease: A Case Report

Cited by 17 publications

References 5 publications

Management of Childhood Urticaria: Current Knowledge and Practical Recommendations

Management of Childhood Urticaria: Current Knowledge and Practical Recommendations

Skin Manifestations and Coeliac Disease in Paediatric Population

Dietary strategies for chronic spontaneous urticaria: an evidence‐based review

Contact Info

Product

Resources

About