Chronic Urticaria After Implantation of a Mitral Annuloplasty Ring in a Nickel-Allergic Patient

Abstract

Tumores gastrointestinales malignos. Oxaliplatino. Reacción de hipersensibilidad a oxaliplatino. Infusión prolongada. Infusión estándar.

Systemic Allergic Contact Dermatitis Due to a GORE CARDIOFORM Septal Occluder Device

“…Nickel exposure is known to induce urticaria in a subset of patients with nickel allergy, and has been previously reported in association with various implants ( 13 ). As in the current case, systemic allergic contact dermatitis to nickel following implantation of an intracardiac device that resolved with explantation has been described ( 14 ). In this prior report, patch testing showed a 3+ reaction to nickel sulfate, whereas other investigations such as serum nickel testing and an evaluation of in vitro nickel elution from the device did not show elevated nickel levels.…”

Mitral Ring Extraction due to Nickel Allergy

“…Skin allergy tests in our patient were positive to nickel. However, mechanisms causing anaphylactic reaction were not demonstrated: food allergy was ruled out, results of viral serologic tests were negative, values for total immunoglobulin E and serum tryptase were within the normal range, basophil activation measured by expression of CD63 yielded negative results, and serum nickel detection was negative [6]. After the nickel nucleus was removed from the mitral annulus, the urticarial rash disappeared completely, demonstrating a clear temporal relationship.…”